HCSGD entry for SALL1

1. General information

Official gene symbolSALL1
Entrez ID6299
Gene full namesal-like 1 (Drosophila)
Other gene symbolsHSAL1 Sal-1 TBS ZNF794
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDA IEAbiological_process
GO:0000792HeterochromatinIDA IEAcellular_component
GO:0001657Ureteric bud developmentISSbiological_process
GO:0001658Branching involved in ureteric bud morphogenesisISSbiological_process
GO:0001822Kidney developmentIMPbiological_process
GO:0001843Neural tube closureIEAbiological_process
GO:0003281Ventricular septum developmentIEA ISSbiological_process
GO:0003337Mesenchymal to epithelial transition involved in metanephros morphogenesisIEPbiological_process
GO:0003677DNA bindingIEA NASmolecular_function
GO:0003682Chromatin bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityNASmolecular_function
GO:0004407Histone deacetylase activityISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006476Protein deacetylationISSbiological_process
GO:0007507Heart developmentIMPbiological_process
GO:0008013Beta-catenin bindingIDAmolecular_function
GO:0008406Gonad developmentIEPbiological_process
GO:0010369ChromocenterIDAcellular_component
GO:0016575Histone deacetylationISSbiological_process
GO:0016581NuRD complexIEA ISScellular_component
GO:0021553Olfactory nerve developmentIEA ISSbiological_process
GO:0021772Olfactory bulb developmentIEAbiological_process
GO:0021889Olfactory bulb interneuron differentiationISSbiological_process
GO:0021983Pituitary gland developmentIEPbiological_process
GO:0030177Positive regulation of Wnt signaling pathwayIDAbiological_process
GO:0030325Adrenal gland developmentIEPbiological_process
GO:0031129Inductive cell-cell signalingIEA ISSbiological_process
GO:0035136Forelimb morphogenesisIEAbiological_process
GO:0035137Hindlimb morphogenesisIEAbiological_process
GO:0042473Outer ear morphogenesisIMPbiological_process
GO:0042733Embryonic digit morphogenesisIMPbiological_process
GO:0045666Positive regulation of neuron differentiationIEAbiological_process
GO:0045879Negative regulation of smoothened signaling pathwayIEAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDA IEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048566Embryonic digestive tract developmentIMPbiological_process
GO:0060173Limb developmentIMPbiological_process
GO:0061034Olfactory bulb mitral cell layer developmentIMPbiological_process
GO:0072073Kidney epithelium developmentISSbiological_process
GO:0072092Ureteric bud invasionIEA ISSbiological_process
GO:2000177Regulation of neural precursor cell proliferationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.55301999920.15959144030.99999024730.7717285819

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1146748460
GSE13712_SHEARDown-0.0645688052
GSE13712_STATICDown-0.0807631268
GSE19018Down-0.6500405590
GSE19899_A1Down-0.4824586123
GSE19899_A2Down-0.7346104573
PubMed_21979375_A1Up1.0771967147
PubMed_21979375_A2Up0.8653724861
GSE35957Down-0.3947881462
GSE36640Down-0.1712800510
GSE54402Up0.4363737120
GSE9593Up0.1923135093
GSE43922Up0.0485324153
GSE24585Down-0.4377029828
GSE37065Down-0.1258252883
GSE28863_A1Up0.0453271311
GSE28863_A2Up0.0807368556
GSE28863_A3Up0.0433458895
GSE28863_A4Up0.0333199631
GSE48662Down-0.0399530231

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-103a-3pMIMAT0000101MIRT027034SequencingFunctional MTI (Weak)20371350
hsa-miR-26b-5pMIMAT0000083MIRT029033MicroarrayFunctional MTI (Weak)19088304
hsa-miR-16-5pMIMAT0000069MIRT031523SequencingFunctional MTI (Weak)20371350
hsa-miR-744-5pMIMAT0004945MIRT037498CLASHFunctional MTI (Weak)23622248
hsa-miR-423-5pMIMAT0004748MIRT038173CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044785CLASHFunctional MTI (Weak)23622248
hsa-let-7e-5pMIMAT0000066MIRT051534CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

23841748Here, using quantitative RT-PCR and flow cytometry [fluorescence-activated cell sorting (FACS)] analysis, we show in VPA-treated primary cultures of human adult and fetal kidney significant reinduction of the renal stem/progenitor markers SIX2, OSR1, SALL1, NCAM, and PSA-NCAM
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