HCSGD entry for SALL1

1. General information

Official gene symbolSALL1
Entrez ID6299
Gene full namesal-like 1 (Drosophila)
Other gene symbolsHSAL1 Sal-1 TBS ZNF794
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDA IEAbiological_process
GO:0000792HeterochromatinIDA IEAcellular_component
GO:0001657Ureteric bud developmentISSbiological_process
GO:0001658Branching involved in ureteric bud morphogenesisISSbiological_process
GO:0001822Kidney developmentIMPbiological_process
GO:0001843Neural tube closureIEAbiological_process
GO:0003281Ventricular septum developmentIEA ISSbiological_process
GO:0003337Mesenchymal to epithelial transition involved in metanephros morphogenesisIEPbiological_process
GO:0003677DNA bindingIEA NASmolecular_function
GO:0003682Chromatin bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityNASmolecular_function
GO:0004407Histone deacetylase activityISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006476Protein deacetylationISSbiological_process
GO:0007507Heart developmentIMPbiological_process
GO:0008013Beta-catenin bindingIDAmolecular_function
GO:0008406Gonad developmentIEPbiological_process
GO:0010369ChromocenterIDAcellular_component
GO:0016575Histone deacetylationISSbiological_process
GO:0016581NuRD complexIEA ISScellular_component
GO:0021553Olfactory nerve developmentIEA ISSbiological_process
GO:0021772Olfactory bulb developmentIEAbiological_process
GO:0021889Olfactory bulb interneuron differentiationISSbiological_process
GO:0021983Pituitary gland developmentIEPbiological_process
GO:0030177Positive regulation of Wnt signaling pathwayIDAbiological_process
GO:0030325Adrenal gland developmentIEPbiological_process
GO:0031129Inductive cell-cell signalingIEA ISSbiological_process
GO:0035136Forelimb morphogenesisIEAbiological_process
GO:0035137Hindlimb morphogenesisIEAbiological_process
GO:0042473Outer ear morphogenesisIMPbiological_process
GO:0042733Embryonic digit morphogenesisIMPbiological_process
GO:0045666Positive regulation of neuron differentiationIEAbiological_process
GO:0045879Negative regulation of smoothened signaling pathwayIEAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDA IEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048566Embryonic digestive tract developmentIMPbiological_process
GO:0060173Limb developmentIMPbiological_process
GO:0061034Olfactory bulb mitral cell layer developmentIMPbiological_process
GO:0072073Kidney epithelium developmentISSbiological_process
GO:0072092Ureteric bud invasionIEA ISSbiological_process
GO:2000177Regulation of neural precursor cell proliferationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.55301999920.15959144030.99999024730.7717285819

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1146748460
GSE13712_SHEARDown-0.0645688052
GSE13712_STATICDown-0.0807631268
GSE19018Down-0.6500405590
GSE19899_A1Down-0.4824586123
GSE19899_A2Down-0.7346104573
PubMed_21979375_A1Up1.0771967147
PubMed_21979375_A2Up0.8653724861
GSE35957Down-0.3947881462
GSE36640Down-0.1712800510
GSE54402Up0.4363737120
GSE9593Up0.1923135093
GSE43922Up0.0485324153
GSE24585Down-0.4377029828
GSE37065Down-0.1258252883
GSE28863_A1Up0.0453271311
GSE28863_A2Up0.0807368556
GSE28863_A3Up0.0433458895
GSE28863_A4Up0.0333199631
GSE48662Down-0.0399530231

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-103a-3pMIMAT0000101MIRT027034SequencingFunctional MTI (Weak)20371350
hsa-miR-26b-5pMIMAT0000083MIRT029033MicroarrayFunctional MTI (Weak)19088304
hsa-miR-16-5pMIMAT0000069MIRT031523SequencingFunctional MTI (Weak)20371350
hsa-miR-744-5pMIMAT0004945MIRT037498CLASHFunctional MTI (Weak)23622248
hsa-miR-423-5pMIMAT0004748MIRT038173CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044785CLASHFunctional MTI (Weak)23622248
hsa-let-7e-5pMIMAT0000066MIRT051534CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

23841748Here, using quantitative RT-PCR and flow cytometry [fluorescence-activated cell sorting (FACS)] analysis, we show in VPA-treated primary cultures of human adult and fetal kidney significant reinduction of the renal stem/progenitor markers SIX2, OSR1, SALL1, NCAM, and PSA-NCAM
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