HCSGD entry for SAFB
1. General information
| Official gene symbol | SAFB |
|---|---|
| Entrez ID | 6294 |
| Gene full name | scaffold attachment factor B |
| Other gene symbols | HAP HET SAF-B1 SAFB1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0001047 | Core promoter binding | IEA | molecular_function |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0003690 | Double-stranded DNA binding | TAS | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006325 | Chromatin organization | TAS | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0030520 | Intracellular estrogen receptor signaling pathway | IEA | biological_process |
| GO:0040007 | Growth | IEA | biological_process |
| GO:0042445 | Hormone metabolic process | IEA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7475800198 | 0.2971104631 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0104643311 |
| GSE13712_SHEAR | Down | -0.1095788151 |
| GSE13712_STATIC | Down | -0.0994187533 |
| GSE19018 | Up | 0.0681630859 |
| GSE19899_A1 | Down | -0.0510500784 |
| GSE19899_A2 | Down | -0.1800527869 |
| PubMed_21979375_A1 | Up | 0.3489282560 |
| PubMed_21979375_A2 | Down | -0.2290886607 |
| GSE35957 | Down | -0.5339920273 |
| GSE36640 | Down | -0.6438899300 |
| GSE54402 | Up | 0.1700970439 |
| GSE9593 | Down | -0.2726206460 |
| GSE43922 | Up | 0.0092271711 |
| GSE24585 | Down | -0.2702461882 |
| GSE37065 | Up | 0.1169960795 |
| GSE28863_A1 | Down | -0.0946508737 |
| GSE28863_A2 | Down | -0.1724847634 |
| GSE28863_A3 | Up | 0.5137159784 |
| GSE28863_A4 | Up | 0.2164234890 |
| GSE48662 | Up | 0.2259372181 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029657 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036307 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-5p | MIMAT0004700 | MIRT038183 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049805 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051734 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052123 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
