HCSGD entry for SAFB


1. General information

Official gene symbolSAFB
Entrez ID6294
Gene full namescaffold attachment factor B
Other gene symbolsHAP HET SAF-B1 SAFB1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0001047Core promoter bindingIEAmolecular_function
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003682Chromatin bindingIEAmolecular_function
GO:0003690Double-stranded DNA bindingTASmolecular_function
GO:0003723RNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006325Chromatin organizationTASbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0030520Intracellular estrogen receptor signaling pathwayIEAbiological_process
GO:0040007GrowthIEAbiological_process
GO:0042445Hormone metabolic processIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.74758001980.29711046310.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0104643311
GSE13712_SHEARDown-0.1095788151
GSE13712_STATICDown-0.0994187533
GSE19018Up0.0681630859
GSE19899_A1Down-0.0510500784
GSE19899_A2Down-0.1800527869
PubMed_21979375_A1Up0.3489282560
PubMed_21979375_A2Down-0.2290886607
GSE35957Down-0.5339920273
GSE36640Down-0.6438899300
GSE54402Up0.1700970439
GSE9593Down-0.2726206460
GSE43922Up0.0092271711
GSE24585Down-0.2702461882
GSE37065Up0.1169960795
GSE28863_A1Down-0.0946508737
GSE28863_A2Down-0.1724847634
GSE28863_A3Up0.5137159784
GSE28863_A4Up0.2164234890
GSE48662Up0.2259372181

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029657MicroarrayFunctional MTI (Weak)19088304
hsa-miR-1229-3pMIMAT0005584MIRT036307CLASHFunctional MTI (Weak)23622248
hsa-miR-331-5pMIMAT0004700MIRT038183CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049805CLASHFunctional MTI (Weak)23622248
hsa-let-7c-5pMIMAT0000064MIRT051734CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT052123CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.