HCSGD entry for RXRG

1. General information

Official gene symbolRXRG
Entrez ID6258
Gene full nameretinoid X receptor, gamma
Other gene symbolsNR2B3 RXRC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003707Steroid hormone receptor activityIEAmolecular_function
GO:00048869-cis retinoic acid receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0007422Peripheral nervous system developmentIEAbiological_process
GO:0007507Heart developmentIEAbiological_process
GO:0007519Skeletal muscle tissue developmentIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0010467Gene expressionTASbiological_process
GO:0030182Neuron differentiationIEAbiological_process
GO:0031641Regulation of myelinationIEAbiological_process
GO:0032526Response to retinoic acidIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.54798454470.92314508950.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0495830558
GSE13712_SHEARUp0.0621864809
GSE13712_STATICUp0.1020610116
GSE19018Up0.0329368102
GSE19899_A1Up0.1080487802
GSE19899_A2Up0.0407078494
PubMed_21979375_A1Down-0.1533238523
PubMed_21979375_A2Down-0.0880150814
GSE35957Up0.1169018935
GSE36640Up0.0931073105
GSE54402Down-0.0454715719
GSE9593Up0.1150028732
GSE43922Up0.0138838903
GSE24585Up0.3651444224
GSE37065Up0.1064319993
GSE28863_A1Down-0.0444951608
GSE28863_A2Up0.1190483755
GSE28863_A3Up0.2252775619
GSE28863_A4Down-0.0098187156
GSE48662Up0.0040909353

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AdapaleneDB00210 APRD00780
EtretinateDB00926 APRD00966

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.