HCSGD entry for RPS27

1. General information

Official gene symbolRPS27
Entrez ID6232
Gene full nameribosomal protein S27
Other gene symbolsMPS-1 MPS1 S27
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000184Nuclear-transcribed mRNA catabolic process, nonsense-mediated decayTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0003677DNA bindingNASmolecular_function
GO:0003735Structural constituent of ribosomeIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005840RibosomeIEA NAScellular_component
GO:0006412TranslationIC IEA NAS TASbiological_process
GO:0006413Translational initiationTASbiological_process
GO:0006414Translational elongationTASbiological_process
GO:0006415Translational terminationTASbiological_process
GO:0006614SRP-dependent cotranslational protein targeting to membraneTASbiological_process
GO:0008270Zinc ion bindingNASmolecular_function
GO:0008283Cell proliferationNASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0019058Viral life cycleTASbiological_process
GO:0019083Viral transcriptionTASbiological_process
GO:0022627Cytosolic small ribosomal subunitIDAcellular_component
GO:0044267Cellular protein metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.92709489760.39318818430.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0840242635
GSE13712_SHEARUp0.0206425436
GSE13712_STATICDown-0.0925794459
GSE19018Down-0.0118138256
GSE19899_A1Up0.0151243963
GSE19899_A2Down-0.0061229511
PubMed_21979375_A1Up0.2917095518
PubMed_21979375_A2Up0.1839273775
GSE35957Down-0.0776674979
GSE36640Down-0.1145122113
GSE54402Up0.0482716938
GSE9593Down-0.2125024960
GSE43922Down-0.0575329490
GSE24585Up0.0655129903
GSE37065Down-0.3264018966
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.4562434012

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT031378ProteomicsFunctional MTI (Weak)18668040
hsa-miR-877-5pMIMAT0004949MIRT037255CLASHFunctional MTI (Weak)23622248
hsa-miR-455-3pMIMAT0004784MIRT037843CLASHFunctional MTI (Weak)23622248
hsa-miR-502-3pMIMAT0004775MIRT037982CLASHFunctional MTI (Weak)23622248
hsa-miR-636MIMAT0003306MIRT039575CLASHFunctional MTI (Weak)23622248
hsa-miR-331-3pMIMAT0000760MIRT043408CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044612CLASHFunctional MTI (Weak)23622248
hsa-miR-100-5pMIMAT0000098MIRT048465CLASHFunctional MTI (Weak)23622248
hsa-miR-20a-5pMIMAT0000075MIRT050605CLASHFunctional MTI (Weak)23622248
hsa-let-7e-5pMIMAT0000066MIRT051425CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.