HCSGD entry for RPS27

1. General information

Official gene symbolRPS27
Entrez ID6232
Gene full nameribosomal protein S27
Other gene symbolsMPS-1 MPS1 S27
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000184Nuclear-transcribed mRNA catabolic process, nonsense-mediated decayTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0003677DNA bindingNASmolecular_function
GO:0003735Structural constituent of ribosomeIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005840RibosomeIEA NAScellular_component
GO:0006412TranslationIC IEA NAS TASbiological_process
GO:0006413Translational initiationTASbiological_process
GO:0006414Translational elongationTASbiological_process
GO:0006415Translational terminationTASbiological_process
GO:0006614SRP-dependent cotranslational protein targeting to membraneTASbiological_process
GO:0008270Zinc ion bindingNASmolecular_function
GO:0008283Cell proliferationNASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0019058Viral life cycleTASbiological_process
GO:0019083Viral transcriptionTASbiological_process
GO:0022627Cytosolic small ribosomal subunitIDAcellular_component
GO:0044267Cellular protein metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.92709489760.39318818430.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0840242635
GSE13712_SHEARUp0.0206425436
GSE13712_STATICDown-0.0925794459
GSE19018Down-0.0118138256
GSE19899_A1Up0.0151243963
GSE19899_A2Down-0.0061229511
PubMed_21979375_A1Up0.2917095518
PubMed_21979375_A2Up0.1839273775
GSE35957Down-0.0776674979
GSE36640Down-0.1145122113
GSE54402Up0.0482716938
GSE9593Down-0.2125024960
GSE43922Down-0.0575329490
GSE24585Up0.0655129903
GSE37065Down-0.3264018966
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.4562434012

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT031378ProteomicsFunctional MTI (Weak)18668040
hsa-miR-877-5pMIMAT0004949MIRT037255CLASHFunctional MTI (Weak)23622248
hsa-miR-455-3pMIMAT0004784MIRT037843CLASHFunctional MTI (Weak)23622248
hsa-miR-502-3pMIMAT0004775MIRT037982CLASHFunctional MTI (Weak)23622248
hsa-miR-636MIMAT0003306MIRT039575CLASHFunctional MTI (Weak)23622248
hsa-miR-331-3pMIMAT0000760MIRT043408CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044612CLASHFunctional MTI (Weak)23622248
hsa-miR-100-5pMIMAT0000098MIRT048465CLASHFunctional MTI (Weak)23622248
hsa-miR-20a-5pMIMAT0000075MIRT050605CLASHFunctional MTI (Weak)23622248
hsa-let-7e-5pMIMAT0000066MIRT051425CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.