HCSGD entry for RPL23A

1. General information

Official gene symbolRPL23A
Entrez ID6147
Gene full nameribosomal protein L23a
Other gene symbolsL23A MDA20
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0000184Nuclear-transcribed mRNA catabolic process, nonsense-mediated decayTASbiological_process
GO:0003735Structural constituent of ribosomeIEA NASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005840RibosomeIEAcellular_component
GO:0006412TranslationIEA NAS TASbiological_process
GO:0006413Translational initiationTASbiological_process
GO:0006414Translational elongationTASbiological_process
GO:0006415Translational terminationTASbiological_process
GO:0006614SRP-dependent cotranslational protein targeting to membraneTASbiological_process
GO:0008283Cell proliferationIMPbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0019058Viral life cycleTASbiological_process
GO:0019083Viral transcriptionTASbiological_process
GO:0019843RRNA bindingIEAmolecular_function
GO:0022625Cytosolic large ribosomal subunitIDA NAScellular_component
GO:0031932TORC2 complexIEA ISScellular_component
GO:0044267Cellular protein metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.90810031530.51339373880.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0188203858
GSE13712_SHEARDown-0.1965705254
GSE13712_STATICDown-0.1878137520
GSE19018Up0.0037893812
GSE19899_A1Up0.0513495509
GSE19899_A2Down-0.0694321228
PubMed_21979375_A1Up0.1758072753
PubMed_21979375_A2Down-0.0188703004
GSE35957Down-0.3405965622
GSE36640Down-0.2205602796
GSE54402Up0.1345289640
GSE9593Down-0.0422123576
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.2074189036
GSE28863_A2Up0.2399663433
GSE28863_A3Down-0.2049492001
GSE28863_A4Up0.1025874111
GSE48662Down-0.2930096205

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Alpha-Hydroxy-Beta-Phenyl-Propionic AcidDB02494 EXPT01733
AnisomycinDB07374 -
PuromycinDB08437 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-877-5pMIMAT0004949MIRT037257CLASHFunctional MTI (Weak)23622248
hsa-miR-423-5pMIMAT0004748MIRT038169CLASHFunctional MTI (Weak)23622248
hsa-miR-769-3pMIMAT0003887MIRT039135CLASHFunctional MTI (Weak)23622248
hsa-miR-671-5pMIMAT0003880MIRT039258CLASHFunctional MTI (Weak)23622248
hsa-miR-193b-3pMIMAT0002819MIRT041229CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.