HCSGD entry for RPL23A
1. General information
| Official gene symbol | RPL23A |
|---|---|
| Entrez ID | 6147 |
| Gene full name | ribosomal protein L23a |
| Other gene symbols | L23A MDA20 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000184 | Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | TAS | biological_process |
| GO:0003735 | Structural constituent of ribosome | IEA NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005840 | Ribosome | IEA | cellular_component |
| GO:0006412 | Translation | IEA NAS TAS | biological_process |
| GO:0006413 | Translational initiation | TAS | biological_process |
| GO:0006414 | Translational elongation | TAS | biological_process |
| GO:0006415 | Translational termination | TAS | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0008283 | Cell proliferation | IMP | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0019058 | Viral life cycle | TAS | biological_process |
| GO:0019083 | Viral transcription | TAS | biological_process |
| GO:0019843 | RRNA binding | IEA | molecular_function |
| GO:0022625 | Cytosolic large ribosomal subunit | IDA NAS | cellular_component |
| GO:0031932 | TORC2 complex | IEA ISS | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9081003153 | 0.5133937388 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0188203858 |
| GSE13712_SHEAR | Down | -0.1965705254 |
| GSE13712_STATIC | Down | -0.1878137520 |
| GSE19018 | Up | 0.0037893812 |
| GSE19899_A1 | Up | 0.0513495509 |
| GSE19899_A2 | Down | -0.0694321228 |
| PubMed_21979375_A1 | Up | 0.1758072753 |
| PubMed_21979375_A2 | Down | -0.0188703004 |
| GSE35957 | Down | -0.3405965622 |
| GSE36640 | Down | -0.2205602796 |
| GSE54402 | Up | 0.1345289640 |
| GSE9593 | Down | -0.0422123576 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.2074189036 |
| GSE28863_A2 | Up | 0.2399663433 |
| GSE28863_A3 | Down | -0.2049492001 |
| GSE28863_A4 | Up | 0.1025874111 |
| GSE48662 | Down | -0.2930096205 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Alpha-Hydroxy-Beta-Phenyl-Propionic Acid | DB02494 | EXPT01733 |
| Anisomycin | DB07374 | - |
| Puromycin | DB08437 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-877-5p | MIMAT0004949 | MIRT037257 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038169 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-769-3p | MIMAT0003887 | MIRT039135 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-671-5p | MIMAT0003880 | MIRT039258 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041229 | CLASH | Functional MTI (Weak) | 23622248 |
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