HCSGD entry for RIT1


1. General information

Official gene symbolRIT1
Entrez ID6016
Gene full nameRas-like without CAAX 1
Other gene symbolsRIBB RIT ROC1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003924GTPase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005516Calmodulin bindingTASmolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0005886Plasma membraneIEAcellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0007265Ras protein signal transductionIDAbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.37027769080.04507432470.99999024730.3991464046

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1291756392
GSE13712_SHEARUp0.1528131546
GSE13712_STATICUp0.1396611610
GSE19018Down-0.5546315733
GSE19899_A1Down-0.2806279571
GSE19899_A2Down-0.2165323753
PubMed_21979375_A1Up0.5256723432
PubMed_21979375_A2Down-0.0930829509
GSE35957Down-0.4857445919
GSE36640Up0.9540876461
GSE54402Down-0.4364310633
GSE9593Down-0.0019668052
GSE43922Down-0.1511993706
GSE24585Up0.9377921401
GSE37065Up0.2186780346
GSE28863_A1Down-0.5593169057
GSE28863_A2Up0.2737599201
GSE28863_A3Down-0.7051656025
GSE28863_A4Down-0.1216990229
GSE48662Down-0.8198632451

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-340-5pMIMAT0004692MIRT019637SequencingFunctional MTI (Weak)20371350
hsa-miR-218-5pMIMAT0000275MIRT024228SequencingFunctional MTI (Weak)20371350
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.