HCSGD entry for RIT1
1. General information
| Official gene symbol | RIT1 |
|---|---|
| Entrez ID | 6016 |
| Gene full name | Ras-like without CAAX 1 |
| Other gene symbols | RIBB RIT ROC1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005516 | Calmodulin binding | TAS | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | TAS | biological_process |
| GO:0007265 | Ras protein signal transduction | IDA | biological_process |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3702776908 | 0.0450743247 | 0.9999902473 | 0.3991464046 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1291756392 |
| GSE13712_SHEAR | Up | 0.1528131546 |
| GSE13712_STATIC | Up | 0.1396611610 |
| GSE19018 | Down | -0.5546315733 |
| GSE19899_A1 | Down | -0.2806279571 |
| GSE19899_A2 | Down | -0.2165323753 |
| PubMed_21979375_A1 | Up | 0.5256723432 |
| PubMed_21979375_A2 | Down | -0.0930829509 |
| GSE35957 | Down | -0.4857445919 |
| GSE36640 | Up | 0.9540876461 |
| GSE54402 | Down | -0.4364310633 |
| GSE9593 | Down | -0.0019668052 |
| GSE43922 | Down | -0.1511993706 |
| GSE24585 | Up | 0.9377921401 |
| GSE37065 | Up | 0.2186780346 |
| GSE28863_A1 | Down | -0.5593169057 |
| GSE28863_A2 | Up | 0.2737599201 |
| GSE28863_A3 | Down | -0.7051656025 |
| GSE28863_A4 | Down | -0.1216990229 |
| GSE48662 | Down | -0.8198632451 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-340-5p | MIMAT0004692 | MIRT019637 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-218-5p | MIMAT0000275 | MIRT024228 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
