HCSGD entry for ALOXE3
1. General information
| Official gene symbol | ALOXE3 |
|---|---|
| Entrez ID | 59344 |
| Gene full name | arachidonate lipoxygenase 3 |
| Other gene symbols | ARCI3 E-LOX eLOX3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006665 | Sphingolipid metabolic process | IDA | biological_process |
| GO:0016702 | Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | IDA IEA | molecular_function |
| GO:0019233 | Sensory perception of pain | ISS | biological_process |
| GO:0019369 | Arachidonic acid metabolic process | IDA | biological_process |
| GO:0019372 | Lipoxygenase pathway | IDA | biological_process |
| GO:0035357 | Peroxisome proliferator activated receptor signaling pathway | ISS | biological_process |
| GO:0043651 | Linoleic acid metabolic process | IDA | biological_process |
| GO:0045444 | Fat cell differentiation | ISS | biological_process |
| GO:0046513 | Ceramide biosynthetic process | ISS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051120 | Hepoxilin A3 synthase activity | IDA | molecular_function |
| GO:0051122 | Hepoxilin biosynthetic process | IDA | biological_process |
| GO:0061436 | Establishment of skin barrier | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1825789750 | 0.9626170662 | 0.8364469892 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0056390443 |
| GSE13712_SHEAR | Up | 0.1729603269 |
| GSE13712_STATIC | Up | 0.0165816063 |
| GSE19018 | Up | 0.0802877210 |
| GSE19899_A1 | Up | 0.1121177498 |
| GSE19899_A2 | Up | 0.1176337890 |
| PubMed_21979375_A1 | Up | 0.7781419380 |
| PubMed_21979375_A2 | Up | 0.2133952869 |
| GSE35957 | Up | 0.0448521360 |
| GSE36640 | Up | 0.0989939295 |
| GSE54402 | Up | 0.2307651930 |
| GSE9593 | Down | -0.0013468932 |
| GSE43922 | Up | 0.0309630577 |
| GSE24585 | Down | -0.0033998247 |
| GSE37065 | Up | 0.0190714843 |
| GSE28863_A1 | Up | 0.0680958919 |
| GSE28863_A2 | Up | 0.1656323541 |
| GSE28863_A3 | Up | 0.3881688009 |
| GSE28863_A4 | Up | 0.0389673189 |
| GSE48662 | Down | -0.0259426628 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
