HCSGD entry for ALOXE3

1. General information

Official gene symbolALOXE3
Entrez ID59344
Gene full namearachidonate lipoxygenase 3
Other gene symbolsARCI3 E-LOX eLOX3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005506Iron ion bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0006665Sphingolipid metabolic processIDAbiological_process
GO:0016702Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygenIDA IEAmolecular_function
GO:0019233Sensory perception of painISSbiological_process
GO:0019369Arachidonic acid metabolic processIDAbiological_process
GO:0019372Lipoxygenase pathwayIDAbiological_process
GO:0035357Peroxisome proliferator activated receptor signaling pathwayISSbiological_process
GO:0043651Linoleic acid metabolic processIDAbiological_process
GO:0045444Fat cell differentiationISSbiological_process
GO:0046513Ceramide biosynthetic processISSbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0051120Hepoxilin A3 synthase activityIDAmolecular_function
GO:0051122Hepoxilin biosynthetic processIDAbiological_process
GO:0061436Establishment of skin barrierISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.18257897500.96261706620.83644698921.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0056390443
GSE13712_SHEARUp0.1729603269
GSE13712_STATICUp0.0165816063
GSE19018Up0.0802877210
GSE19899_A1Up0.1121177498
GSE19899_A2Up0.1176337890
PubMed_21979375_A1Up0.7781419380
PubMed_21979375_A2Up0.2133952869
GSE35957Up0.0448521360
GSE36640Up0.0989939295
GSE54402Up0.2307651930
GSE9593Down-0.0013468932
GSE43922Up0.0309630577
GSE24585Down-0.0033998247
GSE37065Up0.0190714843
GSE28863_A1Up0.0680958919
GSE28863_A2Up0.1656323541
GSE28863_A3Up0.3881688009
GSE28863_A4Up0.0389673189
GSE48662Down-0.0259426628

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.