HCSGD entry for RBBP6


1. General information

Official gene symbolRBBP6
Entrez ID5930
Gene full nameretinoblastoma binding protein 6
Other gene symbolsMY038 P2P-R PACT RBQ-1 SNAMA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001701In utero embryonic developmentIEAbiological_process
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0004842Ubiquitin-protein ligase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005694ChromosomeIEAcellular_component
GO:0005730NucleolusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005815Microtubule organizing centerIEAcellular_component
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0035264Multicellular organism growthIEAbiological_process
GO:0042787Protein ubiquitination involved in ubiquitin-dependent protein catabolic processIDAbiological_process
GO:0048568Embryonic organ developmentIEAbiological_process
GO:0061053Somite developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.16717770980.88787551380.80695453881.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0973741834
GSE13712_SHEARDown-0.0247089305
GSE13712_STATICUp0.0137072915
GSE19018Up0.2573450081
GSE19899_A1Up0.0656790523
GSE19899_A2Up0.3825678482
PubMed_21979375_A1Up0.4690464720
PubMed_21979375_A2Up0.3105469819
GSE35957Up0.0164145428
GSE36640Down-0.3630083763
GSE54402Up0.0652155993
GSE9593Down-0.0811784104
GSE43922Up0.1663620742
GSE24585Down-0.0642327464
GSE37065Up0.1313572242
GSE28863_A1Up0.6358903612
GSE28863_A2Up0.3374149595
GSE28863_A3Down-0.4673414859
GSE28863_A4Up0.1573937521
GSE48662Down-0.1719560438

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1254MIMAT0005905MIRT035852CLASHFunctional MTI (Weak)23622248
hsa-miR-149-5pMIMAT0000450MIRT045398CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT052305CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.