HCSGD entry for RBBP6
1. General information
| Official gene symbol | RBBP6 |
|---|---|
| Entrez ID | 5930 |
| Gene full name | retinoblastoma binding protein 6 |
| Other gene symbols | MY038 P2P-R PACT RBQ-1 SNAMA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001701 | In utero embryonic development | IEA | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005694 | Chromosome | IEA | cellular_component |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005815 | Microtubule organizing center | IEA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0035264 | Multicellular organism growth | IEA | biological_process |
| GO:0042787 | Protein ubiquitination involved in ubiquitin-dependent protein catabolic process | IDA | biological_process |
| GO:0048568 | Embryonic organ development | IEA | biological_process |
| GO:0061053 | Somite development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1671777098 | 0.8878755138 | 0.8069545388 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0973741834 |
| GSE13712_SHEAR | Down | -0.0247089305 |
| GSE13712_STATIC | Up | 0.0137072915 |
| GSE19018 | Up | 0.2573450081 |
| GSE19899_A1 | Up | 0.0656790523 |
| GSE19899_A2 | Up | 0.3825678482 |
| PubMed_21979375_A1 | Up | 0.4690464720 |
| PubMed_21979375_A2 | Up | 0.3105469819 |
| GSE35957 | Up | 0.0164145428 |
| GSE36640 | Down | -0.3630083763 |
| GSE54402 | Up | 0.0652155993 |
| GSE9593 | Down | -0.0811784104 |
| GSE43922 | Up | 0.1663620742 |
| GSE24585 | Down | -0.0642327464 |
| GSE37065 | Up | 0.1313572242 |
| GSE28863_A1 | Up | 0.6358903612 |
| GSE28863_A2 | Up | 0.3374149595 |
| GSE28863_A3 | Down | -0.4673414859 |
| GSE28863_A4 | Up | 0.1573937521 |
| GSE48662 | Down | -0.1719560438 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1254 | MIMAT0005905 | MIRT035852 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045398 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052305 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
