HCSGD entry for PTPRR
1. General information
| Official gene symbol | PTPRR |
|---|---|
| Entrez ID | 5801 |
| Gene full name | protein tyrosine phosphatase, receptor type, R |
| Other gene symbols | EC-PTP PCPTP1 PTP-SL PTPBR7 PTPRQ |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001701 | In utero embryonic development | IEP | biological_process |
| GO:0004725 | Protein tyrosine phosphatase activity | IEA TAS | molecular_function |
| GO:0005001 | Transmembrane receptor protein tyrosine phosphatase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006470 | Protein dephosphorylation | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019901 | Protein kinase binding | IEA ISS | molecular_function |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0033607918 | 0.9729928574 | 0.1571214920 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.0894108297 |
| GSE13712_SHEAR | Up | 1.0373312887 |
| GSE13712_STATIC | Up | 0.5649037113 |
| GSE19018 | Down | -0.0174884896 |
| GSE19899_A1 | Up | 0.3156650852 |
| GSE19899_A2 | Up | 1.2445922213 |
| PubMed_21979375_A1 | Up | 2.0488007676 |
| PubMed_21979375_A2 | Up | 2.7984546574 |
| GSE35957 | Up | 1.1085223416 |
| GSE36640 | Up | 0.0416320268 |
| GSE54402 | Up | 0.5510890457 |
| GSE9593 | Down | -0.0303381766 |
| GSE43922 | Up | 0.1411903742 |
| GSE24585 | Up | 0.1517041390 |
| GSE37065 | Up | 0.1225097673 |
| GSE28863_A1 | Down | -0.3484810172 |
| GSE28863_A2 | Down | -0.0072402420 |
| GSE28863_A3 | Up | 0.0006296415 |
| GSE28863_A4 | Up | 0.0057905128 |
| GSE48662 | Down | -0.3326486247 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-150-5p | MIMAT0000451 | MIRT021209 | Microarray | Functional MTI (Weak) | 20218812 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
