HCSGD entry for PTPRR

1. General information

Official gene symbolPTPRR
Entrez ID5801
Gene full nameprotein tyrosine phosphatase, receptor type, R
Other gene symbolsEC-PTP PCPTP1 PTP-SL PTPBR7 PTPRQ
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001701In utero embryonic developmentIEPbiological_process
GO:0004725Protein tyrosine phosphatase activityIEA TASmolecular_function
GO:0005001Transmembrane receptor protein tyrosine phosphatase activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0006470Protein dephosphorylationTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0019901Protein kinase bindingIEA ISSmolecular_function
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00336079180.97299285740.15712149201.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.0894108297
GSE13712_SHEARUp1.0373312887
GSE13712_STATICUp0.5649037113
GSE19018Down-0.0174884896
GSE19899_A1Up0.3156650852
GSE19899_A2Up1.2445922213
PubMed_21979375_A1Up2.0488007676
PubMed_21979375_A2Up2.7984546574
GSE35957Up1.1085223416
GSE36640Up0.0416320268
GSE54402Up0.5510890457
GSE9593Down-0.0303381766
GSE43922Up0.1411903742
GSE24585Up0.1517041390
GSE37065Up0.1225097673
GSE28863_A1Down-0.3484810172
GSE28863_A2Down-0.0072402420
GSE28863_A3Up0.0006296415
GSE28863_A4Up0.0057905128
GSE48662Down-0.3326486247

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-150-5pMIMAT0000451MIRT021209MicroarrayFunctional MTI (Weak)20218812
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.