HCSGD entry for PTPRD
1. General information
| Official gene symbol | PTPRD |
|---|---|
| Entrez ID | 5789 |
| Gene full name | protein tyrosine phosphatase, receptor type, D |
| Other gene symbols | HPTP HPTPD HPTPDELTA PTPD RPTPDELTA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004725 | Protein tyrosine phosphatase activity | IEA | molecular_function |
| GO:0005001 | Transmembrane receptor protein tyrosine phosphatase activity | TAS | molecular_function |
| GO:0005102 | Receptor binding | ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006470 | Protein dephosphorylation | TAS | biological_process |
| GO:0006796 | Phosphate-containing compound metabolic process | NAS | biological_process |
| GO:0007157 | Heterophilic cell-cell adhesion | ISS | biological_process |
| GO:0007185 | Transmembrane receptor protein tyrosine phosphatase signaling pathway | TAS | biological_process |
| GO:0030182 | Neuron differentiation | ISS | biological_process |
| GO:0035335 | Peptidyl-tyrosine dephosphorylation | TAS | biological_process |
| GO:0050775 | Positive regulation of dendrite morphogenesis | ISS | biological_process |
| GO:0050839 | Cell adhesion molecule binding | ISS | molecular_function |
| GO:0097105 | Presynaptic membrane assembly | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9830584970 | 0.0156038942 | 0.9999902473 | 0.2446159619 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2086474039 |
| GSE13712_SHEAR | Down | -1.4174056277 |
| GSE13712_STATIC | Down | -1.8651487870 |
| GSE19018 | Down | -0.5712080779 |
| GSE19899_A1 | Up | 0.0649034831 |
| GSE19899_A2 | Down | -0.0252344050 |
| PubMed_21979375_A1 | Down | -0.0751110041 |
| PubMed_21979375_A2 | Up | 0.0969851983 |
| GSE35957 | Up | 0.1388810397 |
| GSE36640 | Down | -0.4613578112 |
| GSE54402 | Down | -0.4500502828 |
| GSE9593 | Down | -0.1624999885 |
| GSE43922 | Up | 0.0171527094 |
| GSE24585 | Down | -0.2461604592 |
| GSE37065 | Down | -0.7030701660 |
| GSE28863_A1 | Down | -0.2023648454 |
| GSE28863_A2 | Down | -0.1081886033 |
| GSE28863_A3 | Up | 0.1227972967 |
| GSE28863_A4 | Down | -0.0552947995 |
| GSE48662 | Up | 0.1540333826 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-429 | MIMAT0001536 | MIRT016634 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200a-3p | MIMAT0000682 | MIRT020345 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200c-3p | MIMAT0000617 | MIRT021067 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-141-3p | MIMAT0000432 | MIRT021661 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-1 | MIMAT0000416 | MIRT023978 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-200b-3p | MIMAT0000318 | MIRT024123 | Reporter assay | Functional MTI | 20005803 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-141-3p | MIMAT0000432 | NA | hsa-miR-141 | 20005803 | |||
| hsa-miR-200a-3p | MIMAT0000682 | NA | hsa-miR-200a | 20005803 | |||
| hsa-miR-200b-3p | MIMAT0000318 | NA | hsa-miR-200b | 20005803 | |||
| hsa-miR-429 | MIMAT0001536 | NA | hsa-miR-429 | 20005803 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
