HCSGD entry for PTPRD


1. General information

Official gene symbolPTPRD
Entrez ID5789
Gene full nameprotein tyrosine phosphatase, receptor type, D
Other gene symbolsHPTP HPTPD HPTPDELTA PTPD RPTPDELTA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004725Protein tyrosine phosphatase activityIEAmolecular_function
GO:0005001Transmembrane receptor protein tyrosine phosphatase activityTASmolecular_function
GO:0005102Receptor bindingISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006470Protein dephosphorylationTASbiological_process
GO:0006796Phosphate-containing compound metabolic processNASbiological_process
GO:0007157Heterophilic cell-cell adhesionISSbiological_process
GO:0007185Transmembrane receptor protein tyrosine phosphatase signaling pathwayTASbiological_process
GO:0030182Neuron differentiationISSbiological_process
GO:0035335Peptidyl-tyrosine dephosphorylationTASbiological_process
GO:0050775Positive regulation of dendrite morphogenesisISSbiological_process
GO:0050839Cell adhesion molecule bindingISSmolecular_function
GO:0097105Presynaptic membrane assemblyISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98305849700.01560389420.99999024730.2446159619

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2086474039
GSE13712_SHEARDown-1.4174056277
GSE13712_STATICDown-1.8651487870
GSE19018Down-0.5712080779
GSE19899_A1Up0.0649034831
GSE19899_A2Down-0.0252344050
PubMed_21979375_A1Down-0.0751110041
PubMed_21979375_A2Up0.0969851983
GSE35957Up0.1388810397
GSE36640Down-0.4613578112
GSE54402Down-0.4500502828
GSE9593Down-0.1624999885
GSE43922Up0.0171527094
GSE24585Down-0.2461604592
GSE37065Down-0.7030701660
GSE28863_A1Down-0.2023648454
GSE28863_A2Down-0.1081886033
GSE28863_A3Up0.1227972967
GSE28863_A4Down-0.0552947995
GSE48662Up0.1540333826

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-429MIMAT0001536MIRT016634Reporter assayFunctional MTI20005803
hsa-miR-200a-3pMIMAT0000682MIRT020345Reporter assayFunctional MTI20005803
hsa-miR-200c-3pMIMAT0000617MIRT021067Reporter assayFunctional MTI20005803
hsa-miR-141-3pMIMAT0000432MIRT021661Reporter assayFunctional MTI20005803
hsa-miR-1MIMAT0000416MIRT023978MicroarrayFunctional MTI (Weak)18668037
hsa-miR-200b-3pMIMAT0000318MIRT024123Reporter assayFunctional MTI20005803
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-141-3pMIMAT0000432NAhsa-miR-14120005803
hsa-miR-200a-3pMIMAT0000682NAhsa-miR-200a20005803
hsa-miR-200b-3pMIMAT0000318NAhsa-miR-200b20005803
hsa-miR-429MIMAT0001536NAhsa-miR-42920005803
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.