HCSGD entry for GBA2

1. General information

Official gene symbolGBA2
Entrez ID57704
Gene full nameglucosidase, beta (bile acid) 2
Other gene symbolsSPG46
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIEAcellular_component
GO:0004348Glucosylceramidase activityIEAmolecular_function
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0005790Smooth endoplasmic reticulumTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006665Sphingolipid metabolic processTASbiological_process
GO:0006680Glucosylceramide catabolic processIEAbiological_process
GO:0006687Glycosphingolipid metabolic processTASbiological_process
GO:0008206Bile acid metabolic processIDA TASbiological_process
GO:0008219Cell deathIEAbiological_process
GO:0008422Beta-glucosidase activityIDAmolecular_function
GO:0016021Integral component of membraneIDA IEA NAScellular_component
GO:0016139Glycoside catabolic processIDA NASbiological_process
GO:0021954Central nervous system neuron developmentIMPbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04809693020.72507689680.48513318011.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0533348195
GSE13712_SHEARUp0.9117599564
GSE13712_STATICUp0.3998796038
GSE19018Down-0.2163382679
GSE19899_A1Up0.0053200308
GSE19899_A2Up0.4459524011
PubMed_21979375_A1Up0.6257528561
PubMed_21979375_A2Up0.9176734966
GSE35957Down-0.5477179563
GSE36640Up0.2837614237
GSE54402Up0.4335398183
GSE9593Down-0.2476973305
GSE43922Up0.5410534534
GSE24585Up0.4229455357
GSE37065Up0.1912812475
GSE28863_A1Up0.0579196146
GSE28863_A2Down-0.2105158224
GSE28863_A3Down-0.7637848916
GSE28863_A4Down-0.0357017134
GSE48662Down-0.1295276807

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-455-3pMIMAT0004784MIRT037829CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.