HCSGD entry for GBA2

1. General information

Official gene symbolGBA2
Entrez ID57704
Gene full nameglucosidase, beta (bile acid) 2
Other gene symbolsSPG46
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIEAcellular_component
GO:0004348Glucosylceramidase activityIEAmolecular_function
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0005790Smooth endoplasmic reticulumTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006665Sphingolipid metabolic processTASbiological_process
GO:0006680Glucosylceramide catabolic processIEAbiological_process
GO:0006687Glycosphingolipid metabolic processTASbiological_process
GO:0008206Bile acid metabolic processIDA TASbiological_process
GO:0008219Cell deathIEAbiological_process
GO:0008422Beta-glucosidase activityIDAmolecular_function
GO:0016021Integral component of membraneIDA IEA NAScellular_component
GO:0016139Glycoside catabolic processIDA NASbiological_process
GO:0021954Central nervous system neuron developmentIMPbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04809693020.72507689680.48513318011.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0533348195
GSE13712_SHEARUp0.9117599564
GSE13712_STATICUp0.3998796038
GSE19018Down-0.2163382679
GSE19899_A1Up0.0053200308
GSE19899_A2Up0.4459524011
PubMed_21979375_A1Up0.6257528561
PubMed_21979375_A2Up0.9176734966
GSE35957Down-0.5477179563
GSE36640Up0.2837614237
GSE54402Up0.4335398183
GSE9593Down-0.2476973305
GSE43922Up0.5410534534
GSE24585Up0.4229455357
GSE37065Up0.1912812475
GSE28863_A1Up0.0579196146
GSE28863_A2Down-0.2105158224
GSE28863_A3Down-0.7637848916
GSE28863_A4Down-0.0357017134
GSE48662Down-0.1295276807

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-455-3pMIMAT0004784MIRT037829CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.