HCSGD entry for TAOK1

1. General information

Official gene symbolTAOK1
Entrez ID57551
Gene full nameTAO kinase 1
Other gene symbolsKFC-B MAP3K16 MARKK PSK-2 PSK2 TAO1 hKFC-B hTAOK1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000165MAPK cascadeIBAbiological_process
GO:0000186Activation of MAPKK activityIBAbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0004672Protein kinase activityIEA NASmolecular_function
GO:0004674Protein serine/threonine kinase activityISS NASmolecular_function
GO:0004709MAP kinase kinase kinase activityIBAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEA NASmolecular_function
GO:0005737CytoplasmIBAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006281DNA repairIEAbiological_process
GO:0006468Protein phosphorylationNASbiological_process
GO:0006974Cellular response to DNA damage stimulusIDAbiological_process
GO:0007165Signal transductionIBAbiological_process
GO:0016301Kinase activityNASmolecular_function
GO:0016740Transferase activityNASmolecular_function
GO:0023014Signal transduction by phosphorylationIBAbiological_process
GO:0031572G2 DNA damage checkpointIMPbiological_process
GO:0031577Spindle checkpointIDAbiological_process
GO:0032874Positive regulation of stress-activated MAPK cascadeIMPbiological_process
GO:0035556Intracellular signal transductionIBAbiological_process
GO:0046330Positive regulation of JNK cascadeIDAbiological_process
GO:0051493Regulation of cytoskeleton organizationISSbiological_process
GO:0097194Execution phase of apoptosisIDAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02491808820.94170389800.37201871811.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2560973412
GSE13712_SHEARUp0.1366125622
GSE13712_STATICUp0.0820568913
GSE19018Up0.0133589732
GSE19899_A1Down-0.0210896599
GSE19899_A2Down-0.2472981396
PubMed_21979375_A1Down-0.0008734176
PubMed_21979375_A2Up0.3674844103
GSE35957Up0.5923954022
GSE36640Up0.1044927973
GSE54402Up0.1132935169
GSE9593Up0.3154955067
GSE43922Down-0.0387112608
GSE24585Up0.3491418949
GSE37065Up0.1967820569
GSE28863_A1Up1.0790920061
GSE28863_A2Up1.6012752170
GSE28863_A3Up0.0433450630
GSE28863_A4Up0.0626593135
GSE48662Up0.2694459364

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-425-5pMIMAT0003393MIRT016671SequencingFunctional MTI (Weak)20371350
hsa-miR-142-3pMIMAT0000434MIRT021639MicroarrayFunctional MTI (Weak)17612493
hsa-miR-30b-5pMIMAT0000420MIRT023458SequencingFunctional MTI (Weak)20371350
hsa-miR-96-5pMIMAT0000095MIRT027919SequencingFunctional MTI (Weak)20371350
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.