HCSGD entry for TAOK1
1. General information
| Official gene symbol | TAOK1 |
|---|---|
| Entrez ID | 57551 |
| Gene full name | TAO kinase 1 |
| Other gene symbols | KFC-B MAP3K16 MARKK PSK-2 PSK2 TAO1 hKFC-B hTAOK1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000165 | MAPK cascade | IBA | biological_process |
| GO:0000186 | Activation of MAPKK activity | IBA | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0004672 | Protein kinase activity | IEA NAS | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | ISS NAS | molecular_function |
| GO:0004709 | MAP kinase kinase kinase activity | IBA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA NAS | molecular_function |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0006468 | Protein phosphorylation | NAS | biological_process |
| GO:0006974 | Cellular response to DNA damage stimulus | IDA | biological_process |
| GO:0007165 | Signal transduction | IBA | biological_process |
| GO:0016301 | Kinase activity | NAS | molecular_function |
| GO:0016740 | Transferase activity | NAS | molecular_function |
| GO:0023014 | Signal transduction by phosphorylation | IBA | biological_process |
| GO:0031572 | G2 DNA damage checkpoint | IMP | biological_process |
| GO:0031577 | Spindle checkpoint | IDA | biological_process |
| GO:0032874 | Positive regulation of stress-activated MAPK cascade | IMP | biological_process |
| GO:0035556 | Intracellular signal transduction | IBA | biological_process |
| GO:0046330 | Positive regulation of JNK cascade | IDA | biological_process |
| GO:0051493 | Regulation of cytoskeleton organization | ISS | biological_process |
| GO:0097194 | Execution phase of apoptosis | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0249180882 | 0.9417038980 | 0.3720187181 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2560973412 |
| GSE13712_SHEAR | Up | 0.1366125622 |
| GSE13712_STATIC | Up | 0.0820568913 |
| GSE19018 | Up | 0.0133589732 |
| GSE19899_A1 | Down | -0.0210896599 |
| GSE19899_A2 | Down | -0.2472981396 |
| PubMed_21979375_A1 | Down | -0.0008734176 |
| PubMed_21979375_A2 | Up | 0.3674844103 |
| GSE35957 | Up | 0.5923954022 |
| GSE36640 | Up | 0.1044927973 |
| GSE54402 | Up | 0.1132935169 |
| GSE9593 | Up | 0.3154955067 |
| GSE43922 | Down | -0.0387112608 |
| GSE24585 | Up | 0.3491418949 |
| GSE37065 | Up | 0.1967820569 |
| GSE28863_A1 | Up | 1.0790920061 |
| GSE28863_A2 | Up | 1.6012752170 |
| GSE28863_A3 | Up | 0.0433450630 |
| GSE28863_A4 | Up | 0.0626593135 |
| GSE48662 | Up | 0.2694459364 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-425-5p | MIMAT0003393 | MIRT016671 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-142-3p | MIMAT0000434 | MIRT021639 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT023458 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-96-5p | MIMAT0000095 | MIRT027919 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
