HCSGD entry for MAVS
1. General information
Official gene symbol | MAVS |
---|---|
Entrez ID | 57506 |
Gene full name | mitochondrial antiviral signaling protein |
Other gene symbols | CARDIF IPS-1 IPS1 VISA |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0001934 | Positive regulation of protein phosphorylation | IDA | biological_process |
GO:0002218 | Activation of innate immune response | IMP | biological_process |
GO:0002230 | Positive regulation of defense response to virus by host | IDA IMP | biological_process |
GO:0004871 | Signal transducer activity | IMP | molecular_function |
GO:0005515 | Protein binding | IPI | molecular_function |
GO:0005741 | Mitochondrial outer membrane | IDA TAS | cellular_component |
GO:0005778 | Peroxisomal membrane | IDA | cellular_component |
GO:0007165 | Signal transduction | IMP | biological_process |
GO:0016021 | Integral component of membrane | IEA | cellular_component |
GO:0016032 | Viral process | IEA | biological_process |
GO:0019901 | Protein kinase binding | IPI | molecular_function |
GO:0031966 | Mitochondrial membrane | IDA | cellular_component |
GO:0032480 | Negative regulation of type I interferon production | TAS | biological_process |
GO:0032727 | Positive regulation of interferon-alpha production | IDA IMP | biological_process |
GO:0032728 | Positive regulation of interferon-beta production | IDA IMP | biological_process |
GO:0032757 | Positive regulation of interleukin-8 production | IDA | biological_process |
GO:0032760 | Positive regulation of tumor necrosis factor production | IDA | biological_process |
GO:0033160 | Positive regulation of protein import into nucleus, translocation | IDA | biological_process |
GO:0039529 | RIG-I signaling pathway | IEA | biological_process |
GO:0042742 | Defense response to bacterium | IMP | biological_process |
GO:0042993 | Positive regulation of transcription factor import into nucleus | IDA | biological_process |
GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB signaling | IMP | biological_process |
GO:0045071 | Negative regulation of viral genome replication | IDA | biological_process |
GO:0045087 | Innate immune response | IMP TAS | biological_process |
GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
GO:0050700 | CARD domain binding | IPI | molecular_function |
GO:0051091 | Positive regulation of sequence-specific DNA binding transcription factor activity | IDA | biological_process |
GO:0051607 | Defense response to virus | IDA | biological_process |
GO:0060340 | Positive regulation of type I interferon-mediated signaling pathway | IDA | biological_process |
GO:0071360 | Cellular response to exogenous dsRNA | IMP | biological_process |
GO:0071651 | Positive regulation of chemokine (C-C motif) ligand 5 production | IDA | biological_process |
GO:0071660 | Positive regulation of IP-10 production | IDA | biological_process |
GO:1900063 | Regulation of peroxisome organization | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.2344698948 | 0.7571479921 | 0.9176338037 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Up | 0.0326868154 |
GSE13712_SHEAR | Up | 0.2950335767 |
GSE13712_STATIC | Down | -0.0284205231 |
GSE19018 | Down | -0.1518495781 |
GSE19899_A1 | Down | -0.4708496571 |
GSE19899_A2 | Up | 0.2124097669 |
PubMed_21979375_A1 | Up | 0.2661116376 |
PubMed_21979375_A2 | Up | 0.3964768441 |
GSE35957 | Up | 0.0519622907 |
GSE36640 | Down | -0.0129261983 |
GSE54402 | Up | 0.1333096738 |
GSE9593 | Up | 0.3340886884 |
GSE43922 | Up | 0.0552651429 |
GSE24585 | Up | 0.3163950775 |
GSE37065 | Down | -0.3892457400 |
GSE28863_A1 | Up | 0.4253880132 |
GSE28863_A2 | Up | 0.0961289350 |
GSE28863_A3 | Down | -0.0971411900 |
GSE28863_A4 | Down | -0.0959666008 |
GSE48662 | Up | 0.0724467249 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-155-5p | MIMAT0000646 | MIRT020812 | Proteomics | Functional MTI (Weak) | 18668040 |
hsa-miR-186-5p | MIMAT0000456 | MIRT045289 | CLASH | Functional MTI (Weak) | 23622248 |
hsa-miR-92a-3p | MIMAT0000092 | MIRT049317 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord