HCSGD entry for SLC12A5

1. General information

Official gene symbolSLC12A5
Entrez ID57468
Gene full namesolute carrier family 12 (potassium/chloride transporter), member 5
Other gene symbolsKCC2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005886Plasma membraneTAScellular_component
GO:0006810TransportNASbiological_process
GO:0006811Ion transportTASbiological_process
GO:0006813Potassium ion transportIEAbiological_process
GO:0006873Cellular ion homeostasisNASbiological_process
GO:0007268Synaptic transmissionIEAbiological_process
GO:0007612LearningIEAbiological_process
GO:0015379Potassium:chloride symporter activityIEA NASmolecular_function
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIEA NAScellular_component
GO:0034220Ion transmembrane transportNASbiological_process
GO:0035264Multicellular organism growthIEAbiological_process
GO:0040040Thermosensory behaviorIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043198Dendritic shaftIEAcellular_component
GO:0055085Transmembrane transportIEA TASbiological_process
GO:1902476Chloride transmembrane transportNASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.90784567460.49258985600.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0027843002
GSE13712_SHEARDown-0.0114141519
GSE13712_STATICDown-0.1341822876
GSE19018Up0.0774153715
GSE19899_A1Down-0.0149659496
GSE19899_A2Down-0.1565208652
PubMed_21979375_A1Up0.1243764316
PubMed_21979375_A2Down-0.1093882257
GSE35957Up0.1337167074
GSE36640Up0.0306258184
GSE54402Up0.0356897295
GSE9593Down-0.1749322492
GSE43922Up0.0162634370
GSE24585Down-0.0990093509
GSE37065Up0.0965261319
GSE28863_A1Down-0.1174432232
GSE28863_A2Down-0.1869812833
GSE28863_A3Up0.1694399977
GSE28863_A4Down-0.0062718522
GSE48662Down-0.0228520707

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Potassium ChlorideDB00761 APRD01322
BumetanideDB00887 APRD00294

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.