HCSGD entry for SLC12A5

1. General information

Official gene symbolSLC12A5
Entrez ID57468
Gene full namesolute carrier family 12 (potassium/chloride transporter), member 5
Other gene symbolsKCC2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005886Plasma membraneTAScellular_component
GO:0006810TransportNASbiological_process
GO:0006811Ion transportTASbiological_process
GO:0006813Potassium ion transportIEAbiological_process
GO:0006873Cellular ion homeostasisNASbiological_process
GO:0007268Synaptic transmissionIEAbiological_process
GO:0007612LearningIEAbiological_process
GO:0015379Potassium:chloride symporter activityIEA NASmolecular_function
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIEA NAScellular_component
GO:0034220Ion transmembrane transportNASbiological_process
GO:0035264Multicellular organism growthIEAbiological_process
GO:0040040Thermosensory behaviorIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043198Dendritic shaftIEAcellular_component
GO:0055085Transmembrane transportIEA TASbiological_process
GO:1902476Chloride transmembrane transportNASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.90784567460.49258985600.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0027843002
GSE13712_SHEARDown-0.0114141519
GSE13712_STATICDown-0.1341822876
GSE19018Up0.0774153715
GSE19899_A1Down-0.0149659496
GSE19899_A2Down-0.1565208652
PubMed_21979375_A1Up0.1243764316
PubMed_21979375_A2Down-0.1093882257
GSE35957Up0.1337167074
GSE36640Up0.0306258184
GSE54402Up0.0356897295
GSE9593Down-0.1749322492
GSE43922Up0.0162634370
GSE24585Down-0.0990093509
GSE37065Up0.0965261319
GSE28863_A1Down-0.1174432232
GSE28863_A2Down-0.1869812833
GSE28863_A3Up0.1694399977
GSE28863_A4Down-0.0062718522
GSE48662Down-0.0228520707

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Potassium ChlorideDB00761 APRD01322
BumetanideDB00887 APRD00294

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.