HCSGD entry for JPH3
1. General information
| Official gene symbol | JPH3 |
|---|---|
| Entrez ID | 57338 |
| Gene full name | junctophilin 3 |
| Other gene symbols | CAGL237 HDL2 JP-3 JP3 TNRC22 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007612 | Learning | IEA | biological_process |
| GO:0007613 | Memory | IEA | biological_process |
| GO:0014701 | Junctional sarcoplasmic reticulum membrane | TAS | cellular_component |
| GO:0015278 | Calcium-release channel activity | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0030314 | Junctional membrane complex | IEA | cellular_component |
| GO:0035640 | Exploration behavior | IEA | biological_process |
| GO:0040011 | Locomotion | IEA | biological_process |
| GO:0048168 | Regulation of neuronal synaptic plasticity | IEA | biological_process |
| GO:0050885 | Neuromuscular process controlling balance | IEA | biological_process |
| GO:0060314 | Regulation of ryanodine-sensitive calcium-release channel activity | TAS | biological_process |
| GO:0060402 | Calcium ion transport into cytosol | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6053710155 | 0.7969476464 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0339074476 |
| GSE13712_SHEAR | Down | -0.3604598737 |
| GSE13712_STATIC | Down | -0.1768940301 |
| GSE19018 | Up | 0.0878958350 |
| GSE19899_A1 | Up | 0.0781239137 |
| GSE19899_A2 | Down | -0.1426108314 |
| PubMed_21979375_A1 | Down | -0.0169591098 |
| PubMed_21979375_A2 | Up | 0.1007178699 |
| GSE35957 | Up | 0.1659799856 |
| GSE36640 | Up | 0.0469691344 |
| GSE54402 | Up | 0.0508725614 |
| GSE9593 | Down | -0.1110914795 |
| GSE43922 | Up | 0.2532770476 |
| GSE24585 | Up | 0.3164483488 |
| GSE37065 | Up | 0.0275989821 |
| GSE28863_A1 | Down | -0.0895220785 |
| GSE28863_A2 | Down | -0.1338416145 |
| GSE28863_A3 | Up | 0.2664573330 |
| GSE28863_A4 | Up | 0.1062009859 |
| GSE48662 | Down | -0.0221255645 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 24798380 | Human dermal fibroblast cells from the smoker group showed severe senescence following treatment with HDL2 and HDL3 |
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