HCSGD entry for PSMD11

1. General information

Official gene symbolPSMD11
Entrez ID5717
Gene full nameproteasome (prosome, macropain) 26S subunit, non-ATPase, 11
Other gene symbolsRpn6 S9 p44.5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000082G1/S transition of mitotic cell cycleTASbiological_process
GO:0000209Protein polyubiquitinationTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000502Proteasome complexTAScellular_component
GO:0002474Antigen processing and presentation of peptide antigen via MHC class ITASbiological_process
GO:0002479Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0006511Ubiquitin-dependent protein catabolic processIMPbiological_process
GO:0006521Regulation of cellular amino acid metabolic processTASbiological_process
GO:0006915Apoptotic processTASbiological_process
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0022624Proteasome accessory complexIDA IEAcellular_component
GO:0031145Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic processTASbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0042590Antigen processing and presentation of exogenous peptide antigen via MHC class ITASbiological_process
GO:0042981Regulation of apoptotic processTASbiological_process
GO:0043066Negative regulation of apoptotic processTASbiological_process
GO:0043248Proteasome assemblyIMPbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0048863Stem cell differentiationIMPbiological_process
GO:0051436Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051437Positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051439Regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93097414990.10661702060.99999024730.6251429272

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0154390691
GSE13712_SHEARUp0.0402457246
GSE13712_STATICUp0.2599656577
GSE19018Down-0.1268627909
GSE19899_A1Down-0.0460549364
GSE19899_A2Down-0.5168795163
PubMed_21979375_A1Down-0.3340466704
PubMed_21979375_A2Down-0.7359518349
GSE35957Down-0.1406679627
GSE36640Up0.0282143687
GSE54402Up0.2779399523
GSE9593Down-0.1682505720
GSE43922Down-0.0165885132
GSE24585Down-0.2382284718
GSE37065Up0.0265269326
GSE28863_A1Down-0.0572733961
GSE28863_A2Up0.2273914590
GSE28863_A3Down-0.5679673730
GSE28863_A4Up0.1155229291
GSE48662Down-0.4363279873

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-98-5pMIMAT0000096MIRT027649MicroarrayFunctional MTI (Weak)19088304
hsa-miR-16-5pMIMAT0000069MIRT031677ProteomicsFunctional MTI (Weak)18668040
hsa-miR-1236-3pMIMAT0005591MIRT036255CLASHFunctional MTI (Weak)23622248
hsa-miR-940MIMAT0004983MIRT036621CLASHFunctional MTI (Weak)23622248
hsa-miR-877-3pMIMAT0004950MIRT037010CLASHFunctional MTI (Weak)23622248
hsa-miR-877-5pMIMAT0004949MIRT037338CLASHFunctional MTI (Weak)23622248
hsa-miR-744-5pMIMAT0004945MIRT037727CLASHFunctional MTI (Weak)23622248
hsa-miR-324-5pMIMAT0000761MIRT043061CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044706CLASHFunctional MTI (Weak)23622248
hsa-miR-10b-5pMIMAT0000254MIRT047502CLASHFunctional MTI (Weak)23622248
hsa-miR-93-5pMIMAT0000093MIRT048802CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT048989CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.