HCSGD entry for PSMD11

1. General information

Official gene symbolPSMD11
Entrez ID5717
Gene full nameproteasome (prosome, macropain) 26S subunit, non-ATPase, 11
Other gene symbolsRpn6 S9 p44.5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000082G1/S transition of mitotic cell cycleTASbiological_process
GO:0000209Protein polyubiquitinationTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000502Proteasome complexTAScellular_component
GO:0002474Antigen processing and presentation of peptide antigen via MHC class ITASbiological_process
GO:0002479Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0006511Ubiquitin-dependent protein catabolic processIMPbiological_process
GO:0006521Regulation of cellular amino acid metabolic processTASbiological_process
GO:0006915Apoptotic processTASbiological_process
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0022624Proteasome accessory complexIDA IEAcellular_component
GO:0031145Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic processTASbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0042590Antigen processing and presentation of exogenous peptide antigen via MHC class ITASbiological_process
GO:0042981Regulation of apoptotic processTASbiological_process
GO:0043066Negative regulation of apoptotic processTASbiological_process
GO:0043248Proteasome assemblyIMPbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0048863Stem cell differentiationIMPbiological_process
GO:0051436Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051437Positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051439Regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93097414990.10661702060.99999024730.6251429272

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0154390691
GSE13712_SHEARUp0.0402457246
GSE13712_STATICUp0.2599656577
GSE19018Down-0.1268627909
GSE19899_A1Down-0.0460549364
GSE19899_A2Down-0.5168795163
PubMed_21979375_A1Down-0.3340466704
PubMed_21979375_A2Down-0.7359518349
GSE35957Down-0.1406679627
GSE36640Up0.0282143687
GSE54402Up0.2779399523
GSE9593Down-0.1682505720
GSE43922Down-0.0165885132
GSE24585Down-0.2382284718
GSE37065Up0.0265269326
GSE28863_A1Down-0.0572733961
GSE28863_A2Up0.2273914590
GSE28863_A3Down-0.5679673730
GSE28863_A4Up0.1155229291
GSE48662Down-0.4363279873

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-98-5pMIMAT0000096MIRT027649MicroarrayFunctional MTI (Weak)19088304
hsa-miR-16-5pMIMAT0000069MIRT031677ProteomicsFunctional MTI (Weak)18668040
hsa-miR-1236-3pMIMAT0005591MIRT036255CLASHFunctional MTI (Weak)23622248
hsa-miR-940MIMAT0004983MIRT036621CLASHFunctional MTI (Weak)23622248
hsa-miR-877-3pMIMAT0004950MIRT037010CLASHFunctional MTI (Weak)23622248
hsa-miR-877-5pMIMAT0004949MIRT037338CLASHFunctional MTI (Weak)23622248
hsa-miR-744-5pMIMAT0004945MIRT037727CLASHFunctional MTI (Weak)23622248
hsa-miR-324-5pMIMAT0000761MIRT043061CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044706CLASHFunctional MTI (Weak)23622248
hsa-miR-10b-5pMIMAT0000254MIRT047502CLASHFunctional MTI (Weak)23622248
hsa-miR-93-5pMIMAT0000093MIRT048802CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT048989CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.