HCSGD entry for PSMD9

1. General information

Official gene symbolPSMD9
Entrez ID5715
Gene full nameproteasome (prosome, macropain) 26S subunit, non-ATPase, 9
Other gene symbolsRpn4 p27
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000082G1/S transition of mitotic cell cycleTASbiological_process
GO:0000209Protein polyubiquitinationTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0002474Antigen processing and presentation of peptide antigen via MHC class ITASbiological_process
GO:0002479Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentTASbiological_process
GO:0003713Transcription coactivator activityISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusISScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0005838Proteasome regulatory particleNAScellular_component
GO:0006511Ubiquitin-dependent protein catabolic processNASbiological_process
GO:0006521Regulation of cellular amino acid metabolic processTASbiological_process
GO:0006915Apoptotic processTASbiological_process
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestTASbiological_process
GO:0008540Proteasome regulatory particle, base subcomplexIDAcellular_component
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0031145Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic processTASbiological_process
GO:0032024Positive regulation of insulin secretionISSbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0042590Antigen processing and presentation of exogenous peptide antigen via MHC class ITASbiological_process
GO:0042981Regulation of apoptotic processTASbiological_process
GO:0043066Negative regulation of apoptotic processTASbiological_process
GO:0043425BHLH transcription factor bindingISSmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedISSbiological_process
GO:0046676Negative regulation of insulin secretionISSbiological_process
GO:0051436Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051437Positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051439Regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0070682Proteasome regulatory particle assemblyIMPbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.10493708450.96304496030.67297612671.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1335387095
GSE13712_SHEARDown-0.1130889498
GSE13712_STATICUp0.0875743123
GSE19018Down-0.0098816836
GSE19899_A1Up0.1874527454
GSE19899_A2Up0.4854389173
PubMed_21979375_A1Up0.7480264781
PubMed_21979375_A2Up0.4078001141
GSE35957Down-0.0275607420
GSE36640Up0.3872137796
GSE54402Up0.1823315680
GSE9593Up0.1322383949
GSE43922Up0.0689927578
GSE24585Up0.2381501534
GSE37065Down-0.1429652732
GSE28863_A1Up0.0364875378
GSE28863_A2Up0.0944828954
GSE28863_A3Down-0.2296083417
GSE28863_A4Up0.2546282416
GSE48662Down-0.1121392350

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-130b-3pMIMAT0000691MIRT020196SequencingFunctional MTI (Weak)20371350
hsa-miR-186-5pMIMAT0000456MIRT021122SequencingFunctional MTI (Weak)20371350
hsa-miR-148a-3pMIMAT0000243MIRT025995SequencingFunctional MTI (Weak)20371350
hsa-miR-19b-3pMIMAT0000074MIRT031151SequencingFunctional MTI (Weak)20371350
hsa-let-7b-5pMIMAT0000063MIRT032262ProteomicsFunctional MTI (Weak)18668040
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.