HCSGD entry for PSMD9

1. General information

Official gene symbolPSMD9
Entrez ID5715
Gene full nameproteasome (prosome, macropain) 26S subunit, non-ATPase, 9
Other gene symbolsRpn4 p27
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000082G1/S transition of mitotic cell cycleTASbiological_process
GO:0000209Protein polyubiquitinationTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0002474Antigen processing and presentation of peptide antigen via MHC class ITASbiological_process
GO:0002479Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentTASbiological_process
GO:0003713Transcription coactivator activityISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusISScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0005838Proteasome regulatory particleNAScellular_component
GO:0006511Ubiquitin-dependent protein catabolic processNASbiological_process
GO:0006521Regulation of cellular amino acid metabolic processTASbiological_process
GO:0006915Apoptotic processTASbiological_process
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestTASbiological_process
GO:0008540Proteasome regulatory particle, base subcomplexIDAcellular_component
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0031145Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic processTASbiological_process
GO:0032024Positive regulation of insulin secretionISSbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0042590Antigen processing and presentation of exogenous peptide antigen via MHC class ITASbiological_process
GO:0042981Regulation of apoptotic processTASbiological_process
GO:0043066Negative regulation of apoptotic processTASbiological_process
GO:0043425BHLH transcription factor bindingISSmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedISSbiological_process
GO:0046676Negative regulation of insulin secretionISSbiological_process
GO:0051436Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051437Positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051439Regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0070682Proteasome regulatory particle assemblyIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.10493708450.96304496030.67297612671.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1335387095
GSE13712_SHEARDown-0.1130889498
GSE13712_STATICUp0.0875743123
GSE19018Down-0.0098816836
GSE19899_A1Up0.1874527454
GSE19899_A2Up0.4854389173
PubMed_21979375_A1Up0.7480264781
PubMed_21979375_A2Up0.4078001141
GSE35957Down-0.0275607420
GSE36640Up0.3872137796
GSE54402Up0.1823315680
GSE9593Up0.1322383949
GSE43922Up0.0689927578
GSE24585Up0.2381501534
GSE37065Down-0.1429652732
GSE28863_A1Up0.0364875378
GSE28863_A2Up0.0944828954
GSE28863_A3Down-0.2296083417
GSE28863_A4Up0.2546282416
GSE48662Down-0.1121392350

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-130b-3pMIMAT0000691MIRT020196SequencingFunctional MTI (Weak)20371350
hsa-miR-186-5pMIMAT0000456MIRT021122SequencingFunctional MTI (Weak)20371350
hsa-miR-148a-3pMIMAT0000243MIRT025995SequencingFunctional MTI (Weak)20371350
hsa-miR-19b-3pMIMAT0000074MIRT031151SequencingFunctional MTI (Weak)20371350
hsa-let-7b-5pMIMAT0000063MIRT032262ProteomicsFunctional MTI (Weak)18668040
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.