HCSGD entry for PAK7

1. General information

Official gene symbolPAK7
Entrez ID57144
Gene full namep21 protein (Cdc42/Rac)-activated kinase 7
Other gene symbolsPAK5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleIBAbiological_process
GO:0004702Receptor signaling protein serine/threonine kinase activityIBAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIBAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0006915Apoptotic processTASbiological_process
GO:0007010Cytoskeleton organizationTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0016049Cell growthTASbiological_process
GO:0016477Cell migrationTASbiological_process
GO:0023014Signal transduction by phosphorylationIBAbiological_process
GO:0035556Intracellular signal transductionIBAbiological_process
GO:2001237Negative regulation of extrinsic apoptotic signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82580476810.79114788950.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0544518602
GSE13712_SHEARDown-0.0126736234
GSE13712_STATICUp0.0840223308
GSE19018Down-0.0403650603
GSE19899_A1Up0.0001111940
GSE19899_A2Up0.0691694649
PubMed_21979375_A1Up0.2733626466
PubMed_21979375_A2Down-0.1499692183
GSE35957Up0.1480153136
GSE36640Down-0.0641919032
GSE54402Up0.0011439930
GSE9593Down-0.0320292801
GSE43922Up0.0088629552
GSE24585Down-0.0152180367
GSE37065Up0.0249127354
GSE28863_A1Down-0.0476272587
GSE28863_A2Down-0.0782060868
GSE28863_A3Up0.2820885722
GSE28863_A4Up0.0451056005
GSE48662Up0.0114771192

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.