HCSGD entry for PAK7

1. General information

Official gene symbolPAK7
Entrez ID57144
Gene full namep21 protein (Cdc42/Rac)-activated kinase 7
Other gene symbolsPAK5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleIBAbiological_process
GO:0004702Receptor signaling protein serine/threonine kinase activityIBAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIBAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0006915Apoptotic processTASbiological_process
GO:0007010Cytoskeleton organizationTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0016049Cell growthTASbiological_process
GO:0016477Cell migrationTASbiological_process
GO:0023014Signal transduction by phosphorylationIBAbiological_process
GO:0035556Intracellular signal transductionIBAbiological_process
GO:2001237Negative regulation of extrinsic apoptotic signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82580476810.79114788950.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0544518602
GSE13712_SHEARDown-0.0126736234
GSE13712_STATICUp0.0840223308
GSE19018Down-0.0403650603
GSE19899_A1Up0.0001111940
GSE19899_A2Up0.0691694649
PubMed_21979375_A1Up0.2733626466
PubMed_21979375_A2Down-0.1499692183
GSE35957Up0.1480153136
GSE36640Down-0.0641919032
GSE54402Up0.0011439930
GSE9593Down-0.0320292801
GSE43922Up0.0088629552
GSE24585Down-0.0152180367
GSE37065Up0.0249127354
GSE28863_A1Down-0.0476272587
GSE28863_A2Down-0.0782060868
GSE28863_A3Up0.2820885722
GSE28863_A4Up0.0451056005
GSE48662Up0.0114771192

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.