HCSGD entry for IFNK

1. General information

Official gene symbolIFNK
Entrez ID56832
Gene full nameinterferon, kappa
Other gene symbolsIFNT1 INFE1 RP11-27J8.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002250Adaptive immune responseIBAbiological_process
GO:0002286T cell activation involved in immune responseIBAbiological_process
GO:0002323Natural killer cell activation involved in immune responseIBAbiological_process
GO:0005125Cytokine activityIBAmolecular_function
GO:0005132Type I interferon receptor bindingIDAmolecular_function
GO:0005576Extracellular regionICcellular_component
GO:0005615Extracellular spaceIBAcellular_component
GO:0006355Regulation of transcription, DNA-templatedIDAbiological_process
GO:0006959Humoral immune responseIBAbiological_process
GO:0008285Negative regulation of cell proliferationNASbiological_process
GO:0009615Response to virusIEPbiological_process
GO:0019221Cytokine-mediated signaling pathwayIDAbiological_process
GO:0030101Natural killer cell activationNASbiological_process
GO:0030183B cell differentiationIBAbiological_process
GO:0033141Positive regulation of peptidyl-serine phosphorylation of STAT proteinIBAbiological_process
GO:0042100B cell proliferationIBAbiological_process
GO:0043330Response to exogenous dsRNAIBAbiological_process
GO:0045087Innate immune responseIBAbiological_process
GO:0045089Positive regulation of innate immune responseTASbiological_process
GO:0045343Regulation of MHC class I biosynthetic processIBAbiological_process
GO:0051607Defense response to virusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.59496320810.65386588660.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0011988947
GSE13712_SHEARDown-0.0940243074
GSE13712_STATICUp0.1116816546
GSE19018Up0.2649901689
GSE19899_A1Up0.1182319158
GSE19899_A2Down-0.1370890471
PubMed_21979375_A1Down-0.2528819207
PubMed_21979375_A2Down-0.2467609018
GSE35957Up0.1600074043
GSE36640Down-0.1509647453
GSE54402Up0.0079110625
GSE9593Up0.0479211469
GSE43922Down-0.0189944582
GSE24585Up0.0414402654
GSE37065Up0.0062088146
GSE28863_A1Up0.0838729665
GSE28863_A2Down-0.0040208626
GSE28863_A3Up0.1771231287
GSE28863_A4Down-0.0572618658
GSE48662Up0.0597678298

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.