HCSGD entry for IFNK

1. General information

Official gene symbolIFNK
Entrez ID56832
Gene full nameinterferon, kappa
Other gene symbolsIFNT1 INFE1 RP11-27J8.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002250Adaptive immune responseIBAbiological_process
GO:0002286T cell activation involved in immune responseIBAbiological_process
GO:0002323Natural killer cell activation involved in immune responseIBAbiological_process
GO:0005125Cytokine activityIBAmolecular_function
GO:0005132Type I interferon receptor bindingIDAmolecular_function
GO:0005576Extracellular regionICcellular_component
GO:0005615Extracellular spaceIBAcellular_component
GO:0006355Regulation of transcription, DNA-templatedIDAbiological_process
GO:0006959Humoral immune responseIBAbiological_process
GO:0008285Negative regulation of cell proliferationNASbiological_process
GO:0009615Response to virusIEPbiological_process
GO:0019221Cytokine-mediated signaling pathwayIDAbiological_process
GO:0030101Natural killer cell activationNASbiological_process
GO:0030183B cell differentiationIBAbiological_process
GO:0033141Positive regulation of peptidyl-serine phosphorylation of STAT proteinIBAbiological_process
GO:0042100B cell proliferationIBAbiological_process
GO:0043330Response to exogenous dsRNAIBAbiological_process
GO:0045087Innate immune responseIBAbiological_process
GO:0045089Positive regulation of innate immune responseTASbiological_process
GO:0045343Regulation of MHC class I biosynthetic processIBAbiological_process
GO:0051607Defense response to virusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.59496320810.65386588660.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0011988947
GSE13712_SHEARDown-0.0940243074
GSE13712_STATICUp0.1116816546
GSE19018Up0.2649901689
GSE19899_A1Up0.1182319158
GSE19899_A2Down-0.1370890471
PubMed_21979375_A1Down-0.2528819207
PubMed_21979375_A2Down-0.2467609018
GSE35957Up0.1600074043
GSE36640Down-0.1509647453
GSE54402Up0.0079110625
GSE9593Up0.0479211469
GSE43922Down-0.0189944582
GSE24585Up0.0414402654
GSE37065Up0.0062088146
GSE28863_A1Up0.0838729665
GSE28863_A2Down-0.0040208626
GSE28863_A3Up0.1771231287
GSE28863_A4Down-0.0572618658
GSE48662Up0.0597678298

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.