HCSGD entry for CYP26B1

1. General information

Official gene symbolCYP26B1
Entrez ID56603
Gene full namecytochrome P450, family 26, subfamily B, polypeptide 1
Other gene symbolsCYP26A2 P450RAI-2 P450RAI2 RHFCA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001709Cell fate determinationIEA ISSbiological_process
GO:0001972Retinoic acid bindingIDAmolecular_function
GO:0005506Iron ion bindingIEAmolecular_function
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006766Vitamin metabolic processTASbiological_process
GO:0006805Xenobiotic metabolic processTASbiological_process
GO:0007140Male meiosisIEA ISSbiological_process
GO:0007283SpermatogenesisIEA ISSbiological_process
GO:0008401Retinoic acid 4-hydroxylase activityIDA IEAmolecular_function
GO:0009954Proximal/distal pattern formationIEA ISSbiological_process
GO:0010628Positive regulation of gene expressionIEAbiological_process
GO:0016705Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygenIEAmolecular_function
GO:0020037Heme bindingIEA NASmolecular_function
GO:0030326Embryonic limb morphogenesisIEA ISSbiological_process
GO:0034653Retinoic acid catabolic processIDA IEAbiological_process
GO:0043587Tongue morphogenesisIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0048384Retinoic acid receptor signaling pathwayIEAbiological_process
GO:0048387Negative regulation of retinoic acid receptor signaling pathwayTASbiological_process
GO:0055114Oxidation-reduction processIDAbiological_process
GO:0060349Bone morphogenesisIMPbiological_process
GO:0071300Cellular response to retinoic acidIEAbiological_process
GO:2001037Positive regulation of tongue muscle cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00026813570.99844200450.04524102561.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0887083402
GSE13712_SHEARUp0.0090810901
GSE13712_STATICUp0.4696237717
GSE19018Up0.1603821627
GSE19899_A1Up1.6520357992
GSE19899_A2Up3.1742178867
PubMed_21979375_A1Up3.0290797384
PubMed_21979375_A2Up3.7495432258
GSE35957Up2.3095283681
GSE36640Up0.3847942381
GSE54402Up1.6660459122
GSE9593Up0.1338795747
GSE43922Up0.4680804303
GSE24585Up0.2585902282
GSE37065Down-0.0212479772
GSE28863_A1Up0.0464276090
GSE28863_A2Up0.4404486391
GSE28863_A3Up0.3186257077
GSE28863_A4Up0.0744628331
GSE48662Up0.0544373667

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-103a-3pMIMAT0000101MIRT027171SequencingFunctional MTI (Weak)20371350
hsa-miR-16-5pMIMAT0000069MIRT031931SequencingFunctional MTI (Weak)20371350
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.