HCSGD entry for CYP26B1

1. General information

Official gene symbolCYP26B1
Entrez ID56603
Gene full namecytochrome P450, family 26, subfamily B, polypeptide 1
Other gene symbolsCYP26A2 P450RAI-2 P450RAI2 RHFCA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001709Cell fate determinationIEA ISSbiological_process
GO:0001972Retinoic acid bindingIDAmolecular_function
GO:0005506Iron ion bindingIEAmolecular_function
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006766Vitamin metabolic processTASbiological_process
GO:0006805Xenobiotic metabolic processTASbiological_process
GO:0007140Male meiosisIEA ISSbiological_process
GO:0007283SpermatogenesisIEA ISSbiological_process
GO:0008401Retinoic acid 4-hydroxylase activityIDA IEAmolecular_function
GO:0009954Proximal/distal pattern formationIEA ISSbiological_process
GO:0010628Positive regulation of gene expressionIEAbiological_process
GO:0016705Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygenIEAmolecular_function
GO:0020037Heme bindingIEA NASmolecular_function
GO:0030326Embryonic limb morphogenesisIEA ISSbiological_process
GO:0034653Retinoic acid catabolic processIDA IEAbiological_process
GO:0043587Tongue morphogenesisIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0048384Retinoic acid receptor signaling pathwayIEAbiological_process
GO:0048387Negative regulation of retinoic acid receptor signaling pathwayTASbiological_process
GO:0055114Oxidation-reduction processIDAbiological_process
GO:0060349Bone morphogenesisIMPbiological_process
GO:0071300Cellular response to retinoic acidIEAbiological_process
GO:2001037Positive regulation of tongue muscle cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00026813570.99844200450.04524102561.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0887083402
GSE13712_SHEARUp0.0090810901
GSE13712_STATICUp0.4696237717
GSE19018Up0.1603821627
GSE19899_A1Up1.6520357992
GSE19899_A2Up3.1742178867
PubMed_21979375_A1Up3.0290797384
PubMed_21979375_A2Up3.7495432258
GSE35957Up2.3095283681
GSE36640Up0.3847942381
GSE54402Up1.6660459122
GSE9593Up0.1338795747
GSE43922Up0.4680804303
GSE24585Up0.2585902282
GSE37065Down-0.0212479772
GSE28863_A1Up0.0464276090
GSE28863_A2Up0.4404486391
GSE28863_A3Up0.3186257077
GSE28863_A4Up0.0744628331
GSE48662Up0.0544373667

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-103a-3pMIMAT0000101MIRT027171SequencingFunctional MTI (Weak)20371350
hsa-miR-16-5pMIMAT0000069MIRT031931SequencingFunctional MTI (Weak)20371350
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.