HCSGD entry for KLK6

1. General information

Official gene symbolKLK6
Entrez ID5653
Gene full namekallikrein-related peptidase 6
Other gene symbolsBssp Klk7 PRSS18 PRSS9 SP59 hK6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004252Serine-type endopeptidase activityIDA IEA NASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIDAcellular_component
GO:0005730NucleolusIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0007417Central nervous system developmentNASbiological_process
GO:0009611Response to woundingNASbiological_process
GO:0010975Regulation of neuron projection developmentIEAbiological_process
GO:0016540Protein autoprocessingNASbiological_process
GO:0030574Collagen catabolic processNASbiological_process
GO:0042246Tissue regenerationNASbiological_process
GO:0042445Hormone metabolic processNASbiological_process
GO:0042552MyelinationNASbiological_process
GO:0042982Amyloid precursor protein metabolic processNASbiological_process
GO:0045595Regulation of cell differentiationNASbiological_process
GO:0045745Positive regulation of G-protein coupled receptor protein signaling pathwayIDAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.66504171190.62612787510.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0173914649
GSE13712_SHEARDown-0.3655034582
GSE13712_STATICDown-0.0923497596
GSE19018Up0.0666668856
GSE19899_A1Up0.1718519048
GSE19899_A2Up0.2195444330
PubMed_21979375_A1Up0.2313290132
PubMed_21979375_A2Down-0.0765793628
GSE35957Down-0.0910999650
GSE36640Down-0.0028014827
GSE54402Down-0.0089726090
GSE9593Up0.0029621243
GSE43922Up0.1345676450
GSE24585Down-0.3806779825
GSE37065Down-0.2286331476
GSE28863_A1Up0.0559121671
GSE28863_A2Down-0.0402806903
GSE28863_A3Up0.3353000661
GSE28863_A4Up0.0482795140
GSE48662Up0.0326740504

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

BenzamidineDB03127 EXPT00669

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7f-5pMIMAT0000067MIRT004678ELISA//Luciferase reporter assay//qRT-PCRFunctional MTI18627289
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.