HCSGD entry for ALLC
1. General information
| Official gene symbol | ALLC |
|---|---|
| Entrez ID | 55821 |
| Gene full name | allantoicase |
| Other gene symbols | ALC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000256 | Allantoin catabolic process | IEA | biological_process |
| GO:0004037 | Allantoicase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8156331826 | 0.6107639451 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0055281629 |
| GSE13712_SHEAR | Down | -0.4545397144 |
| GSE13712_STATIC | Down | -0.1616802094 |
| GSE19018 | Up | 0.0292363856 |
| GSE19899_A1 | Down | -0.0359170623 |
| GSE19899_A2 | Down | -0.0212723872 |
| PubMed_21979375_A1 | Down | -0.0523063215 |
| PubMed_21979375_A2 | Down | -0.1707039228 |
| GSE35957 | Up | 0.1835137276 |
| GSE36640 | Down | -0.0174371521 |
| GSE54402 | Down | -0.0151974203 |
| GSE9593 | Up | 0.0314081243 |
| GSE43922 | Up | 0.1026438270 |
| GSE24585 | Up | 0.0276430725 |
| GSE37065 | Down | -0.0595224846 |
| GSE28863_A1 | Up | 0.0731210262 |
| GSE28863_A2 | Up | 0.0522872171 |
| GSE28863_A3 | Up | 0.2574708186 |
| GSE28863_A4 | Up | 0.1110154192 |
| GSE48662 | Down | -0.0307237674 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 17622567 | 8 years of age administered a twice daily supplement of alpha-lipoic acid (LA) and acetyl-L-carnitine (ALC) over approximately 2 months made significantly fewer errors in reaching the learning criterion on two landmark discrimination tasks compared to controls administered a methylcellulose placebo |
| 17622567 | The improved performance on the landmark task of dogs supplemented with LA + ALC provides evidence of the effectiveness of this supplement in improving discrimination and allocentric spatial learning |
| 17622567 | We suggest that long-term maintenance on LA and ALC may be effective in attenuating age-associated cognitive decline by slowing the rate of mitochondrial decay and cellular aging |
| 6194235 | In the adults, the levels of Hb Ala + b and Hb Alc determined by Bio-Rex 70 chromatography also showed an increase with increasing red cell age |
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