HCSGD entry for ALLC


1. General information

Official gene symbolALLC
Entrez ID55821
Gene full nameallantoicase
Other gene symbolsALC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000256Allantoin catabolic processIEAbiological_process
GO:0004037Allantoicase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.81563318260.61076394510.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0055281629
GSE13712_SHEARDown-0.4545397144
GSE13712_STATICDown-0.1616802094
GSE19018Up0.0292363856
GSE19899_A1Down-0.0359170623
GSE19899_A2Down-0.0212723872
PubMed_21979375_A1Down-0.0523063215
PubMed_21979375_A2Down-0.1707039228
GSE35957Up0.1835137276
GSE36640Down-0.0174371521
GSE54402Down-0.0151974203
GSE9593Up0.0314081243
GSE43922Up0.1026438270
GSE24585Up0.0276430725
GSE37065Down-0.0595224846
GSE28863_A1Up0.0731210262
GSE28863_A2Up0.0522872171
GSE28863_A3Up0.2574708186
GSE28863_A4Up0.1110154192
GSE48662Down-0.0307237674

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

176225678 years of age administered a twice daily supplement of alpha-lipoic acid (LA) and acetyl-L-carnitine (ALC) over approximately 2 months made significantly fewer errors in reaching the learning criterion on two landmark discrimination tasks compared to controls administered a methylcellulose placebo
17622567The improved performance on the landmark task of dogs supplemented with LA + ALC provides evidence of the effectiveness of this supplement in improving discrimination and allocentric spatial learning
17622567We suggest that long-term maintenance on LA and ALC may be effective in attenuating age-associated cognitive decline by slowing the rate of mitochondrial decay and cellular aging
6194235In the adults, the levels of Hb Ala + b and Hb Alc determined by Bio-Rex 70 chromatography also showed an increase with increasing red cell age
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