HCSGD entry for DRAM1


1. General information

Official gene symbolDRAM1
Entrez ID55332
Gene full nameDNA-damage regulated autophagy modulator 1
Other gene symbolsDRAM
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005737CytoplasmIDAcellular_component
GO:0005764LysosomeIDAcellular_component
GO:0005765Lysosomal membraneIEAcellular_component
GO:0006914AutophagyIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0030262Apoptotic nuclear changesIDAbiological_process
GO:0097194Execution phase of apoptosisICbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06490685380.02194202730.54911526350.2856193086

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.9382120544
GSE13712_SHEARUp0.4712177258
GSE13712_STATICUp0.6802226887
GSE19018Down-0.7301496330
GSE19899_A1Down-1.6658724186
GSE19899_A2Down-0.1205053291
PubMed_21979375_A1Down-1.9626361097
PubMed_21979375_A2Down-0.0308066195
GSE35957Up0.2655325668
GSE36640Up1.2946287022
GSE54402Down-1.6688901025
GSE9593Up0.9896199032
GSE43922Down-0.3484314481
GSE24585Up0.4394817408
GSE37065Up0.3686427528
GSE28863_A1Down-0.0140537842
GSE28863_A2Up0.4466173175
GSE28863_A3Down-0.5227606801
GSE28863_A4Up0.1946174666
GSE48662Up0.5471044187

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT004906MicroarrayFunctional MTI (Weak)15685193
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.