HCSGD entry for DRAM1
1. General information
| Official gene symbol | DRAM1 |
|---|---|
| Entrez ID | 55332 |
| Gene full name | DNA-damage regulated autophagy modulator 1 |
| Other gene symbols | DRAM |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005764 | Lysosome | IDA | cellular_component |
| GO:0005765 | Lysosomal membrane | IEA | cellular_component |
| GO:0006914 | Autophagy | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030262 | Apoptotic nuclear changes | IDA | biological_process |
| GO:0097194 | Execution phase of apoptosis | IC | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0649068538 | 0.0219420273 | 0.5491152635 | 0.2856193086 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.9382120544 |
| GSE13712_SHEAR | Up | 0.4712177258 |
| GSE13712_STATIC | Up | 0.6802226887 |
| GSE19018 | Down | -0.7301496330 |
| GSE19899_A1 | Down | -1.6658724186 |
| GSE19899_A2 | Down | -0.1205053291 |
| PubMed_21979375_A1 | Down | -1.9626361097 |
| PubMed_21979375_A2 | Down | -0.0308066195 |
| GSE35957 | Up | 0.2655325668 |
| GSE36640 | Up | 1.2946287022 |
| GSE54402 | Down | -1.6688901025 |
| GSE9593 | Up | 0.9896199032 |
| GSE43922 | Down | -0.3484314481 |
| GSE24585 | Up | 0.4394817408 |
| GSE37065 | Up | 0.3686427528 |
| GSE28863_A1 | Down | -0.0140537842 |
| GSE28863_A2 | Up | 0.4466173175 |
| GSE28863_A3 | Down | -0.5227606801 |
| GSE28863_A4 | Up | 0.1946174666 |
| GSE48662 | Up | 0.5471044187 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT004906 | Microarray | Functional MTI (Weak) | 15685193 |
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