HCSGD entry for KIRREL
1. General information
| Official gene symbol | KIRREL |
|---|---|
| Entrez ID | 55243 |
| Gene full name | kin of IRRE like (Drosophila) |
| Other gene symbols | NEPH1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001933 | Negative regulation of protein phosphorylation | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0005911 | Cell-cell junction | IDA | cellular_component |
| GO:0007588 | Excretion | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016337 | Cell-cell adhesion | IEA | biological_process |
| GO:0017022 | Myosin binding | IPI | molecular_function |
| GO:0030838 | Positive regulation of actin filament polymerization | IEA | biological_process |
| GO:0043198 | Dendritic shaft | IEA | cellular_component |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4509281828 | 0.5742098135 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0609943930 |
| GSE13712_SHEAR | Down | -0.0194050975 |
| GSE13712_STATIC | Up | 0.1015910485 |
| GSE19018 | Down | -0.1017770546 |
| GSE19899_A1 | Down | -0.2020014002 |
| GSE19899_A2 | Up | 0.0477144949 |
| PubMed_21979375_A1 | Down | -0.4035633093 |
| PubMed_21979375_A2 | Up | 0.7075635228 |
| GSE35957 | Down | -0.1947187962 |
| GSE36640 | Up | 0.1903777095 |
| GSE54402 | Up | 0.1376757201 |
| GSE9593 | Up | 0.2467151635 |
| GSE43922 | Down | -0.0456918042 |
| GSE24585 | Down | -0.2624138419 |
| GSE37065 | Down | -0.0885892061 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.9018557213 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017050 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-99b-3p | MIMAT0004678 | MIRT038527 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040202 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
