HCSGD entry for KIRREL


1. General information

Official gene symbolKIRREL
Entrez ID55243
Gene full namekin of IRRE like (Drosophila)
Other gene symbolsNEPH1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001933Negative regulation of protein phosphorylationIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIDA TAScellular_component
GO:0005911Cell-cell junctionIDAcellular_component
GO:0007588ExcretionIEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016337Cell-cell adhesionIEAbiological_process
GO:0017022Myosin bindingIPImolecular_function
GO:0030838Positive regulation of actin filament polymerizationIEAbiological_process
GO:0043198Dendritic shaftIEAcellular_component
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.45092818280.57420981350.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0609943930
GSE13712_SHEARDown-0.0194050975
GSE13712_STATICUp0.1015910485
GSE19018Down-0.1017770546
GSE19899_A1Down-0.2020014002
GSE19899_A2Up0.0477144949
PubMed_21979375_A1Down-0.4035633093
PubMed_21979375_A2Up0.7075635228
GSE35957Down-0.1947187962
GSE36640Up0.1903777095
GSE54402Up0.1376757201
GSE9593Up0.2467151635
GSE43922Down-0.0456918042
GSE24585Down-0.2624138419
GSE37065Down-0.0885892061
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.9018557213

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017050MicroarrayFunctional MTI (Weak)18185580
hsa-miR-99b-3pMIMAT0004678MIRT038527CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT040202CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.