HCSGD entry for FANCI
1. General information
| Official gene symbol | FANCI |
|---|---|
| Entrez ID | 55215 |
| Gene full name | Fanconi anemia, complementation group I |
| Other gene symbols | KIAA1794 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006281 | DNA repair | IEA TAS | biological_process |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0031398 | Positive regulation of protein ubiquitination | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9192803617 | 0.0001320353 | 0.9999902473 | 0.0202052326 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.6509852130 |
| GSE13712_SHEAR | Down | -0.0625448470 |
| GSE13712_STATIC | Down | -0.2409846924 |
| GSE19018 | Up | 0.0650113681 |
| GSE19899_A1 | Down | -0.9363973914 |
| GSE19899_A2 | Down | -3.0589516077 |
| PubMed_21979375_A1 | Down | -1.7448151496 |
| PubMed_21979375_A2 | Down | -2.5989964271 |
| GSE35957 | Down | -1.6473254430 |
| GSE36640 | Down | -3.2544783539 |
| GSE54402 | Down | -0.7705823540 |
| GSE9593 | Down | -1.0425609632 |
| GSE43922 | Down | -1.4042530137 |
| GSE24585 | Up | 0.1314578880 |
| GSE37065 | Down | -0.6170513669 |
| GSE28863_A1 | Down | -0.5543661917 |
| GSE28863_A2 | Up | 1.0927722730 |
| GSE28863_A3 | Down | -0.4416501508 |
| GSE28863_A4 | Up | 0.4692098378 |
| GSE48662 | Down | -1.4198314913 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016311 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-1 | MIMAT0000416 | MIRT023519 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026117 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030685 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-505-3p | MIMAT0002876 | MIRT041018 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051849 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
