HCSGD entry for FANCI


1. General information

Official gene symbolFANCI
Entrez ID55215
Gene full nameFanconi anemia, complementation group I
Other gene symbolsKIAA1794
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006281DNA repairIEA TASbiological_process
GO:0007049Cell cycleIEAbiological_process
GO:0031398Positive regulation of protein ubiquitinationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91928036170.00013203530.99999024730.0202052326

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.6509852130
GSE13712_SHEARDown-0.0625448470
GSE13712_STATICDown-0.2409846924
GSE19018Up0.0650113681
GSE19899_A1Down-0.9363973914
GSE19899_A2Down-3.0589516077
PubMed_21979375_A1Down-1.7448151496
PubMed_21979375_A2Down-2.5989964271
GSE35957Down-1.6473254430
GSE36640Down-3.2544783539
GSE54402Down-0.7705823540
GSE9593Down-1.0425609632
GSE43922Down-1.4042530137
GSE24585Up0.1314578880
GSE37065Down-0.6170513669
GSE28863_A1Down-0.5543661917
GSE28863_A2Up1.0927722730
GSE28863_A3Down-0.4416501508
GSE28863_A4Up0.4692098378
GSE48662Down-1.4198314913

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT016311MicroarrayFunctional MTI (Weak)20304954
hsa-miR-1MIMAT0000416MIRT023519ProteomicsFunctional MTI (Weak)18668040
hsa-miR-192-5pMIMAT0000222MIRT026117MicroarrayFunctional MTI (Weak)19074876
hsa-miR-21-5pMIMAT0000076MIRT030685MicroarrayFunctional MTI (Weak)18591254
hsa-miR-505-3pMIMAT0002876MIRT041018CLASHFunctional MTI (Weak)23622248
hsa-let-7c-5pMIMAT0000064MIRT051849CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.