HCSGD entry for NADSYN1


1. General information

Official gene symbolNADSYN1
Entrez ID55191
Gene full nameNAD synthetase 1
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003952NAD+ synthase (glutamine-hydrolyzing) activityIEA TASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0006766Vitamin metabolic processTASbiological_process
GO:0006767Water-soluble vitamin metabolic processTASbiological_process
GO:0006807Nitrogen compound metabolic processIEAbiological_process
GO:0009435NAD biosynthetic processIEAbiological_process
GO:0016810Hydrolase activity, acting on carbon-nitrogen (but not peptide) bondsIEAmolecular_function
GO:0019674NAD metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.89432252950.25712486990.99999024730.9720455407

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0300470426
GSE13712_SHEARUp0.0658813488
GSE13712_STATICUp0.1759658917
GSE19018Up0.1250380908
GSE19899_A1Down-0.2722965954
GSE19899_A2Down-0.1932236473
PubMed_21979375_A1Up0.0949368544
PubMed_21979375_A2Up0.0173670063
GSE35957Up0.1944334537
GSE36640Up0.2740234822
GSE54402Down-0.2185243206
GSE9593Down-0.0238743740
GSE43922Down-0.3438451028
GSE24585Down-0.1772512976
GSE37065Down-0.0902245733
GSE28863_A1Down-0.0002605948
GSE28863_A2Down-0.0332103280
GSE28863_A3Down-0.2693952423
GSE28863_A4Down-0.1293995283
GSE48662Up0.1587779137

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Glutamic AcidDB00142 NUTR00027

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.