HCSGD entry for NADSYN1
1. General information
| Official gene symbol | NADSYN1 |
|---|---|
| Entrez ID | 55191 |
| Gene full name | NAD synthetase 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003952 | NAD+ synthase (glutamine-hydrolyzing) activity | IEA TAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0006807 | Nitrogen compound metabolic process | IEA | biological_process |
| GO:0009435 | NAD biosynthetic process | IEA | biological_process |
| GO:0016810 | Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | IEA | molecular_function |
| GO:0019674 | NAD metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8943225295 | 0.2571248699 | 0.9999902473 | 0.9720455407 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0300470426 |
| GSE13712_SHEAR | Up | 0.0658813488 |
| GSE13712_STATIC | Up | 0.1759658917 |
| GSE19018 | Up | 0.1250380908 |
| GSE19899_A1 | Down | -0.2722965954 |
| GSE19899_A2 | Down | -0.1932236473 |
| PubMed_21979375_A1 | Up | 0.0949368544 |
| PubMed_21979375_A2 | Up | 0.0173670063 |
| GSE35957 | Up | 0.1944334537 |
| GSE36640 | Up | 0.2740234822 |
| GSE54402 | Down | -0.2185243206 |
| GSE9593 | Down | -0.0238743740 |
| GSE43922 | Down | -0.3438451028 |
| GSE24585 | Down | -0.1772512976 |
| GSE37065 | Down | -0.0902245733 |
| GSE28863_A1 | Down | -0.0002605948 |
| GSE28863_A2 | Down | -0.0332103280 |
| GSE28863_A3 | Down | -0.2693952423 |
| GSE28863_A4 | Down | -0.1293995283 |
| GSE48662 | Up | 0.1587779137 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Glutamic Acid | DB00142 | NUTR00027 |

