HCSGD entry for PLEKHB2
1. General information
| Official gene symbol | PLEKHB2 |
|---|---|
| Entrez ID | 55041 |
| Gene full name | pleckstrin homology domain containing, family B (evectins) member 2 |
| Other gene symbols | EVT2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0055038 | Recycling endosome membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0192281486 | 0.9840804567 | 0.3378532043 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3871118378 |
| GSE13712_SHEAR | Up | 0.1082951562 |
| GSE13712_STATIC | Up | 0.1967666575 |
| GSE19018 | Up | 0.2816916465 |
| GSE19899_A1 | Up | 0.4506756546 |
| GSE19899_A2 | Up | 0.6664220944 |
| PubMed_21979375_A1 | Up | 0.5727943227 |
| PubMed_21979375_A2 | Up | 0.4327825704 |
| GSE35957 | Up | 0.0041398063 |
| GSE36640 | Up | 0.5830877856 |
| GSE54402 | Up | 0.4007401007 |
| GSE9593 | Up | 0.5028072834 |
| GSE43922 | Up | 0.4646265979 |
| GSE24585 | Up | 0.1683690644 |
| GSE37065 | Up | 0.1947704955 |
| GSE28863_A1 | Down | -0.3102184962 |
| GSE28863_A2 | Up | 0.1775339302 |
| GSE28863_A3 | Down | -0.4333275913 |
| GSE28863_A4 | Down | -0.0884139676 |
| GSE48662 | Down | -0.0881830212 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT002755 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-1 | MIMAT0000416 | MIRT002755 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036970 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-500a-5p | MIMAT0004773 | MIRT038002 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040315 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042958 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-185-5p | MIMAT0000455 | MIRT045384 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047688 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | NA | hsa-miR-1 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
