HCSGD entry for CHCHD3

1. General information

Official gene symbolCHCHD3
Entrez ID54927
Gene full namecoiled-coil-helix-coiled-coil-helix domain containing 3
Other gene symbolsMINOS3 PPP1R22
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0001227RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcriptionIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIDA ISScellular_component
GO:0005743Mitochondrial inner membraneISScellular_component
GO:0006366Transcription from RNA polymerase II promoterIDAbiological_process
GO:0007007Inner mitochondrial membrane organizationIMPbiological_process
GO:0008053Mitochondrial fusionIMPbiological_process
GO:0019902Phosphatase bindingIDAmolecular_function
GO:0032947Protein complex scaffoldISSmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91877527450.11367651310.99999024730.6463770793

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2546302346
GSE13712_SHEARUp0.0231447585
GSE13712_STATICDown-0.1407156472
GSE19018Down-0.2434325502
GSE19899_A1Down-0.1624220291
GSE19899_A2Down-0.0180526192
PubMed_21979375_A1Down-0.4310612962
PubMed_21979375_A2Down-0.2547060194
GSE35957Down-0.3835305096
GSE36640Down-0.3250617790
GSE54402Up0.1214405411
GSE9593Down-0.0859815683
GSE43922Down-0.2247272538
GSE24585Down-0.0861647760
GSE37065Up0.0395989894
GSE28863_A1Down-0.2485029387
GSE28863_A2Up0.3824877548
GSE28863_A3Down-0.0647669064
GSE28863_A4Up0.1678549723
GSE48662Down-0.6262067249

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-423-3pMIMAT0001340MIRT042475CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.